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Protein
Submitted name:

Pancreatic adenocarcinoma upregulated factor

Gene

PAUF

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • blood vessel endothelial cell proliferation involved in sprouting angiogenesis Source: UniProtKB
  • cell migration involved in sprouting angiogenesis Source: UniProtKB
  • positive regulation of protein phosphorylation Source: UniProtKB
  • positive regulation of vascular permeability Source: UniProtKB
  • protein localization to adherens junction Source: UniProtKB
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Pancreatic adenocarcinoma upregulated factorImported
Gene namesi
Name:PAUFImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 4040Sequence analysisAdd
BLAST
Chaini41 – 196156Sequence analysisPRO_5002930779Add
BLAST

Proteomic databases

PaxDbiC3PTT6.
PRIDEiC3PTT6.

Expressioni

Gene expression databases

BgeeiC3PTT6.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
PNMA1Q8ND903EBI-3505892,EBI-302345
SGTAO437653EBI-3505892,EBI-347996
TLR2O606033EBI-3505892,EBI-973722
UBQLN1Q9UMX03EBI-3505892,EBI-741480
UBQLN1Q9UMX0-23EBI-3505892,EBI-10173939

Protein-protein interaction databases

IntActiC3PTT6. 16 interactions.
MINTiMINT-8413264.
STRINGi9606.ENSP00000371715.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini38 – 173136Jacalin-type lectinInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410JCVC. Eukaryota.
ENOG41115HP. LUCA.

Family and domain databases

Gene3Di2.100.10.30. 1 hit.
InterProiIPR001229. Jacalin-like_lectin_dom.
[Graphical view]
PfamiPF01419. Jacalin. 1 hit.
[Graphical view]
SMARTiSM00915. Jacalin. 1 hit.
[Graphical view]
SUPFAMiSSF51101. SSF51101. 1 hit.
PROSITEiPS51752. JACALIN_LECTIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C3PTT6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWRVPGTTRR PVTGESPGMH RPEAMLLLLT LALLGGPTWA GKMYGPGGGK
60 70 80 90 100
YFSTTEDYDH EITGLRVSVG LLLVKSVQVK LGDSWDVKLG ALGGNTQEVT
110 120 130 140 150
LQPGEYITKV FVAFQAFLRG MVMYTSKDRY FYFGKLDGQI SSAYPSQEGQ
160 170 180 190
VLVGIYGQYQ LLGIKSIGFE WNYPLEEPTT EPPVNLTYSA NSPVGR
Length:196
Mass (Da):21,567
Last modified:June 16, 2009 - v1
Checksum:i090C9C973F510E5A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF067313 mRNA. Translation: ABM92915.1.
UniGeneiHs.105887.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF067313 mRNA. Translation: ABM92915.1.
UniGeneiHs.105887.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiC3PTT6. 16 interactions.
MINTiMINT-8413264.
STRINGi9606.ENSP00000371715.

Proteomic databases

PaxDbiC3PTT6.
PRIDEiC3PTT6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410JCVC. Eukaryota.
ENOG41115HP. LUCA.

Miscellaneous databases

NextBioi35482587.

Gene expression databases

BgeeiC3PTT6.

Family and domain databases

Gene3Di2.100.10.30. 1 hit.
InterProiIPR001229. Jacalin-like_lectin_dom.
[Graphical view]
PfamiPF01419. Jacalin. 1 hit.
[Graphical view]
SMARTiSM00915. Jacalin. 1 hit.
[Graphical view]
SUPFAMiSSF51101. SSF51101. 1 hit.
PROSITEiPS51752. JACALIN_LECTIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Identification of a pancreatic adenocarcinoma upregulated factor (PAUF)."
    Koh S.S., Lee Y., Song S.Y., Kim S.-A.
    Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiC3PTT6_HUMAN
AccessioniPrimary (citable) accession number: C3PTT6
Entry historyi
Integrated into UniProtKB/TrEMBL: June 16, 2009
Last sequence update: June 16, 2009
Last modified: April 13, 2016
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.