Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Corynebacterium aurimucosum (strain ATCC 700975 / DSM 44827 / CN-1) (Corynebacterium nigricans)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei132 – 1321UniRule annotation
Active sitei544 – 5441UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciCAUR548476:GH9E-536-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:cauri_0522Imported
OrganismiCorynebacterium aurimucosum (strain ATCC 700975 / DSM 44827 / CN-1) (Corynebacterium nigricans)Imported
Taxonomic identifieri548476 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
ProteomesiUP000002077 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi169292.cauri_0522.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C3PLB5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTPAPEQVR EDIRFLGRVL GRVIAQQEGE DVFELVESTR RMAFDIAHGD
60 70 80 90 100
AKPEDLVAIF RDLDITKVNL VARAFSYFAL IANLAEDLDD ESVEAPVSLR
110 120 130 140 150
KTFAKLKEEG VAPADAASVI RGAHVAPVLT AHPTETRRRT VFDTQTRIKT
160 170 180 190 200
LLKESHRGGD MAAIEKEMYL RMTLLWQTAL IRIARPTLED EIDVGLRYYK
210 220 230 240 250
LSLLDQVPAL NRAIRHAMRE TFGQQLPDSP VVRPGSWIGG DHDGNPFVNE
260 270 280 290 300
HTLTYATRKA AATVLQYYAD ELGELERELS LSDRYSSSSK ELGALADASH
310 320 330 340 350
NDEKSRVDEP YRRAIFGIRK KVLARLEGEA SPSAYASPEE LKRDLDVIDR
360 370 380 390 400
SLRQFNDDII ADDRLARLRS AVTTFGFHLS TLDMRQNSES FENVLTEIFA
410 420 430 440 450
AARITPDYRA LGEEEKVALL VRELQTNRPL LFPGTEKEFT EDTAKELGIF
460 470 480 490 500
RAAARAVRDF GPKSVSHCII SMTGTVSDIL EPMVLLKEVG LGQVDVVPLF
510 520 530 540 550
ETIEDLKAGA SILEKLWQMP VYREHLRSRG DVQEVMLGYS DSNKDGGYLQ
560 570 580 590 600
ANWALYDAEL ALVELCVRHG VELRLAHGRG GAVGRGGGPT YDAILAQPKG
610 620 630 640 650
AVSGSVRITE QGEVISAKYG APETARRHLE AFISGALEAS LLDTEPIADP
660 670 680 690 700
ERAYEIMREL ADLSGTAYRQ LVDDPGFIAY FTQSTPLHEI GELNLGSRPT
710 720 730 740 750
SRKQTTAITD LRAIPWVLSW SQSRTNIPGW FGVGSAVTAW VQQAGGDEEK
760 770 780 790 800
RWEELRELYR TWPFFRSVFA NMAQVMAKAE MQLARLYANL VDDKETADRI
810 820 830 840 850
FGLISVEFER TREVYLKVTG NADLVSENQR QARSLKRRYP YLLPLNAIQL
860 870 880
ELLRRYRRGD DQFLVSKTIQ VTMNGLATAL RNAG
Length:884
Mass (Da):98,875
Last modified:June 16, 2009 - v1
Checksum:iEEA2440586877A9A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001601 Genomic DNA. Translation: ACP32119.1.
RefSeqiWP_010189403.1. NZ_ACLH01000061.1.
YP_002834057.1. NC_012590.1.

Genome annotation databases

EnsemblBacteriaiACP32119; ACP32119; cauri_0522.
KEGGicar:cauri_0522.
PATRICi21477004. VBICorAur68407_0549.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001601 Genomic DNA. Translation: ACP32119.1.
RefSeqiWP_010189403.1. NZ_ACLH01000061.1.
YP_002834057.1. NC_012590.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi169292.cauri_0522.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACP32119; ACP32119; cauri_0522.
KEGGicar:cauri_0522.
PATRICi21477004. VBICorAur68407_0549.

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciCAUR548476:GH9E-536-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence and lifestyle of black-pigmented Corynebacterium aurimucosum ATCC 700975 (formerly C. nigricans CN-1) isolated from a vaginal swab of a woman with spontaneous abortion."
    Trost E., Gotker S., Schneider J., Schneiker-Bekel S., Szczepanowski R., Tilker A., Viehoever P., Arnold W., Bekel T., Blom J., Gartemann K.H., Linke B., Goesmann A., Puhler A., Shukla S.K., Tauch A.
    BMC Genomics 11:91-91(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700975 / DSM 44827 / CN-1Imported.

Entry informationi

Entry nameiC3PLB5_CORA7
AccessioniPrimary (citable) accession number: C3PLB5
Entry historyi
Integrated into UniProtKB/TrEMBL: June 16, 2009
Last sequence update: June 16, 2009
Last modified: April 1, 2015
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.