C3PL50 (GLMM_CORA7) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	cauri_0457

Organism

Corynebacterium aurimucosum (strain ATCC 700975 / DSM 44827 / CN-1) (Corynebacterium nigricans) [Complete proteome] [HAMAP]

Taxonomic identifier

548476 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	447 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 447	447	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_1000185362
Sites
	Active site	104	1	Phosphoserine intermediate By similarity
	Metal binding	104	1	Magnesium; via phosphate group By similarity
	Metal binding	243	1	Magnesium By similarity
	Metal binding	245	1	Magnesium By similarity
	Metal binding	247	1	Magnesium By similarity
Amino acid modifications
	Modified residue	104	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	C3PL50 [UniParc]. Last modified June 16, 2009. Version 1. Checksum: 890FD679FEE4D43D	FASTA	447	47,018
	10 20 30 40 50 60 MTRLFGTDGV RGLANKKLTP ILALRLGQAA AEVLTSDRES YERRPLAIIG RDPRVSGEML 70 80 90 100 110 120 DAAIASGLAS RGVDVVRVGV LPTPAIAFLT DDFGADLGVM ISASHNPMPD NGIKFFSAGG 130 140 150 160 170 180 KKLPDEVEDR IQAAMDNLTE DGPTATKIGR IISEAPDGRE RYLKHLAEVV TTDLSGIKVV 190 200 210 220 230 240 VDTANGAASK VAPQAYEAAG AEVVAIHNKP NAFNINEDCG STHIEKTQEA VVEHGADLGL 250 260 270 280 290 300 AHDGDADRCL AVDAEGNVVD GDQIMAILAV GMKEENDLRF NTLVATVMSN LGLKLAMQEQ 310 320 330 340 350 360 GIDIKETAVG DRYVLEELNR GDFSLGGEQS GHVVLPDDCT TGDGTLTGLS IMARMAKSGK 370 380 390 400 410 420 SLKELASVMT VLPQVLINVP VSDKAVILNA PEVKEAIAAA EAELGETGRV LLRPSGTEEL 430 440 FRVMVEAAEK EQARKVAGKL AAVVAAV

References

[1]

"Complete genome sequence and lifestyle of black-pigmented Corynebacterium aurimucosum ATCC 700975 (formerly C. nigricans CN-1) isolated from a vaginal swab of a woman with spontaneous abortion." Trost E., Gotker S., Schneider J., Schneiker-Bekel S., Szczepanowski R., Tilker A., Viehoever P., Arnold W., Bekel T., Blom J., Gartemann K.H., Linke B., Goesmann A., Puhler A., Shukla S.K., Tauch A. BMC Genomics 11:91-91(2010) [PubMed: 20137072] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700975 / DSM 44827 / CN-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001601 Genomic DNA. Translation: ACP32054.1.
RefSeq	YP_002833992.1. NC_012590.1.
3D structure databases
ProteinModelPortal	C3PL50.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7799675.
GenomeReviews	Gene locus cauri_0457 in contig CP001601_GR.
KEGG	car:cauri_0457.
PATRIC	21476874. VBICorAur68407_0484.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	GVGSTHL.
ProtClustDB	PRK14318.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_CORA7

Accession

Primary (citable) accession number: C3PL50

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	June 16, 2009
Last modified:	January 25, 2012
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program