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C3PH13 (TRUB_CORA7) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
tRNA pseudouridine synthase B
EC=5.4.99.25
Alternative name(s):
tRNA pseudouridine(55) synthase
Short name=Psi55 synthase
tRNA pseudouridylate synthase
tRNA-uridine isomerase
Gene names
Name:truB
Ordered Locus Names:cauri_1524
OrganismCorynebacterium aurimucosum (strain ATCC 700975 / DSM 44827 / CN-1) (Corynebacterium nigricans) [Complete proteome] [HAMAP]
Taxonomic identifier548476 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium ›

Protein attributes

Sequence length297 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs By similarity. HAMAP-Rule MF_01080

Catalytic activity

tRNA uridine55 = tRNA pseudouridine55. HAMAP-Rule MF_01080

Sequence similarities

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.

Ontologies

Keywords
   Biological processtRNA processing
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtRNA pseudouridine synthesis

Inferred from electronic annotation. Source: HAMAP

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: InterPro

pseudouridine synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 297297tRNA pseudouridine synthase B HAMAP-Rule MF_01080
PRO_1000149822

Sites

Active site441Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
C3PH13 [UniParc].

Last modified June 16, 2009. Version 1.
Checksum: AD5CE4390CC47060

FASTA29731,844
        10         20         30         40         50         60 
MTDPLERSGL VVVDKPAGMT SHDVVGKLRR FFRTRKVGHA GTLDPMATGV LVVGIERGTK 

        70         80         90        100        110        120 
FLAHMVASTK AYDATIRLGT ATHTDDAEGE ATWGEPATAV EDSAIAREIA ALTGDIMQRP 

       130        140        150        160        170        180 
AAVSAIKVDG KRAHERVRAG EEVELPARPV TVSRFDILAT RREGEFIDLD VSVACSSGTY 

       190        200        210        220        230        240 
IRSLARDLGE ALGVGGHLTA LRRTEVGPFR LDDAHPLDAL EDSPELSLSL DEALARSYPV 

       250        260        270        280        290 
LEVTDEEAQA LAMGKWLEPR GLKGTYAAVD PQGRSIALIQ EKGKRLATVF VARPSTL

« Hide

References

[1]"Complete genome sequence and lifestyle of black-pigmented Corynebacterium aurimucosum ATCC 700975 (formerly C. nigricans CN-1) isolated from a vaginal swab of a woman with spontaneous abortion."
Trost E., Gotker S., Schneider J., Schneiker-Bekel S., Szczepanowski R., Tilker A., Viehoever P., Arnold W., Bekel T., Blom J., Gartemann K.H., Linke B., Goesmann A., Puhler A., Shukla S.K., Tauch A.
BMC Genomics 11:91-91(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700975 / DSM 44827 / CN-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001601 Genomic DNA. Translation: ACP33117.1.
RefSeqYP_002835055.1. NC_012590.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING169292.cauri_1524.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACP33117; ACP33117; cauri_1524.
GeneID7800803.
KEGGcar:cauri_1524.
PATRIC21479084. VBICorAur68407_1562.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0130.
HOGENOMHOG000231225.
KOK03177.
OMAHATKISG.
ProtClustDBPRK03287.

Enzyme and pathway databases

BioCycCAUR548476:GH9E-1522-MONOMER.

Family and domain databases

HAMAPMF_01080. TruB_bact.
InterProIPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR015947. PUA-like_domain.
IPR015225. tRNA_psdUridine_synth_fam2_C.
IPR014780. tRNA_psdUridine_synth_TruB.
[Graphical view]
PANTHERPTHR13767. PTHR13767. 1 hit.
PfamPF09142. TruB_C. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMSSF55120. PsdUridine_synth_cat_dom. 1 hit.
SSF88697. PUA-like. 1 hit.
TIGRFAMsTIGR00431. TruB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTRUB_CORA7
AccessionPrimary (citable) accession number: C3PH13
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: June 16, 2009
Last modified: May 1, 2013
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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