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C3PG40 (PGK_CORA7) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:cauri_1201
OrganismCorynebacterium aurimucosum (strain ATCC 700975 / DSM 44827 / CN-1) (Corynebacterium nigricans) [Complete proteome] [HAMAP]
Taxonomic identifier548476 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium

Protein attributes

Sequence length405 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 405405Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_1000192820

Regions

Nucleotide binding361 – 3644ATP By similarity
Region24 – 263Substrate binding By similarity
Region63 – 664Substrate binding By similarity

Sites

Binding site401Substrate By similarity
Binding site1221Substrate By similarity
Binding site1621Substrate By similarity
Binding site2121ATP By similarity
Binding site3311ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
C3PG40 [UniParc].

Last modified June 16, 2009. Version 1.
Checksum: 7414534527844044

FASTA40542,525
        10         20         30         40         50         60 
MAFKTLDDLL AEGVSGRHVL VRSDFNVPLD DEGNITDSGR ITASLPTIKA LIEGGAKVIL 

        70         80         90        100        110        120 
SAHLGRPKGE VNPKYSLAPV AEALSEALDQ YVALAGDVSG EDAHERANGL NDGDVLLLEN 

       130        140        150        160        170        180 
VRFDPRETSK DEAERGTFAD ELVALAADNG AFVSDGFGVV HRAQASVYDV AKRLPAYAGK 

       190        200        210        220        230        240 
LVQKEVETLA AVAEKPEHPY VVVLGGAKVS DKLGVIEALA GKADKVIIGG GMCYTLLAAQ 

       250        260        270        280        290        300 
GYNVQDSLLQ EDQIDNCKEL LERFGDKIVL PVDLVAATEF DAQAENKVVA LDGIPEGWQS 

       310        320        330        340        350        360 
LDIGPESVKK FDEVIASSKT VFWNGPMGVF EMEAFSKGTA GVAQSIIDAT AKNGSFTVVG 

       370        380        390        400 
GGDSAASVRL LGLDEEGFSH ISTGGGASLE FLEGKELPGV KVLEA 

« Hide

References

[1]"Complete genome sequence and lifestyle of black-pigmented Corynebacterium aurimucosum ATCC 700975 (formerly C. nigricans CN-1) isolated from a vaginal swab of a woman with spontaneous abortion."
Trost E., Gotker S., Schneider J., Schneiker-Bekel S., Szczepanowski R., Tilker A., Viehoever P., Arnold W., Bekel T., Blom J., Gartemann K.H., Linke B., Goesmann A., Puhler A., Shukla S.K., Tauch A.
BMC Genomics 11:91-91(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700975 / DSM 44827 / CN-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001601 Genomic DNA. Translation: ACP32794.1.
RefSeqYP_002834732.1. NC_012590.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING169292.cauri_1201.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACP32794; ACP32794; cauri_1201.
GeneID7800055.
KEGGcar:cauri_1201.
PATRIC21478400. VBICorAur68407_1235.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227108.
KOK00927.
OMAHASVYDI.
OrthoDBEOG64N9Z0.

Enzyme and pathway databases

BioCycCAUR548476:GH9E-1226-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_CORA7
AccessionPrimary (citable) accession number: C3PG40
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: June 16, 2009
Last modified: June 11, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways