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C3PFN8 (SYR_CORA7) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:cauri_1047
OrganismCorynebacterium aurimucosum (strain ATCC 700975 / DSM 44827 / CN-1) (Corynebacterium nigricans) [Complete proteome] [HAMAP]
Taxonomic identifier548476 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium

Protein attributes

Sequence length553 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 553553Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000198889

Regions

Motif130 – 14011"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
C3PFN8 [UniParc].

Last modified June 16, 2009. Version 1.
Checksum: 70843BF7C0E33BD5

FASTA55359,394
        10         20         30         40         50         60 
MNPEDLSVLI KNTAAAVLTE HELDASVLPE TVTVERPRNP EHGDYATNLA LQVAKKAGAQ 

        70         80         90        100        110        120 
PRELAQWLAD ALAGNDAIDE ASIAGPGFLN IRLAAAAQGA IVAQVLNAGA DFGSNTTYQG 

       130        140        150        160        170        180 
KKINLEFVSA NPTGPIHLGG TRWAAVGDSL GRVLEASGAE VTREYYFNDH GGQIDRFARS 

       190        200        210        220        230        240 
LVAAAKGEPT PEDGYGGGYI KEIAQGVLEQ NPGALDGSDA EVQEAFRSAG VEMMFAQIKE 

       250        260        270        280        290        300 
SLHEFGVDFD VYFHENSLFE SGAVEKSIQK LKDNGKLYEA EGAWWLKSTE YGDDKDRVVI 

       310        320        330        340        350        360 
KSDGNAAYIA GDIAYVADKF DRGHDLAIYM LGADHHGYIA RLRASAQALG YDPDAVEVLI 

       370        380        390        400        410        420 
GQMVNLVRDG KAVKMSKRAG TVITLDDLVE AIGVDGARYS LVRSSVDSSL DIDLGLWASQ 

       430        440        450        460        470        480 
SADNPVYYVQ YGHARICSIL RKAAELGFDT AALADAPLDL LTHDKEGDLI RTLGEFPEVV 

       490        500        510        520        530        540 
ATAATLREPH RIARYAEELA AVFHRFYDQC QVLPKAGEET EPIHSARLAL ASATRQVMSN 

       550 
ALTTVGVSAP EKM 

« Hide

References

[1]"Complete genome sequence and lifestyle of black-pigmented Corynebacterium aurimucosum ATCC 700975 (formerly C. nigricans CN-1) isolated from a vaginal swab of a woman with spontaneous abortion."
Trost E., Gotker S., Schneider J., Schneiker-Bekel S., Szczepanowski R., Tilker A., Viehoever P., Arnold W., Bekel T., Blom J., Gartemann K.H., Linke B., Goesmann A., Puhler A., Shukla S.K., Tauch A.
BMC Genomics 11:91-91(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700975 / DSM 44827 / CN-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001601 Genomic DNA. Translation: ACP32642.1.
RefSeqYP_002834580.1. NC_012590.1.

3D structure databases

ProteinModelPortalC3PFN8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING169292.cauri_1047.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACP32642; ACP32642; cauri_1047.
GeneID7799750.
KEGGcar:cauri_1047.
PATRIC21478086. VBICorAur68407_1081.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMANPNGPLH.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycCAUR548476:GH9E-1070-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_CORA7
AccessionPrimary (citable) accession number: C3PFN8
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: June 16, 2009
Last modified: April 16, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries