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C3PAI2 (C3PAI2_BACAA) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
Name:icd EMBL ACQ49570.1
Ordered Locus Names:BAA_4849 EMBL ACQ49570.1
OrganismBacillus anthracis (strain A0248) [Complete proteome] [HAMAP] EMBL ACQ49570.1
Taxonomic identifier592021 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group

Protein attributes

Sequence length430 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
C3PAI2 [UniParc].

Last modified June 16, 2009. Version 1.
Checksum: 2238E99660A705F3

FASTA43046,973
        10         20         30         40         50         60 
MTTGEKITVT NGVMNVPNNP IIPFIEGDGI GPDIWAAASR VLEAAVEKAY DGEKKIVWKE 

        70         80         90        100        110        120 
VLAGEKAFNQ TGEWLPEETL NLIREYLIAI KGPLTTPVGG GIRSLNVALR QELDLYVCLR 

       130        140        150        160        170        180 
PVRYFEGVPS PVKRPEDTDM VIFRENTEDI YAGIEYAQGS PEAEKVLAFL KEAMGVNKIR 

       190        200        210        220        230        240 
FPETSGIGIK PISEEGTKRL VRAAIQYAIN EKRSSVTLVH KGNIMKFTEG AFKNWGYEVA 

       250        260        270        280        290        300 
EQEFGDKVFT WAEYDRIVEK DGKDAANKAM ADAEVAGKII VKDSIADIFL QQILTRPREF 

       310        320        330        340        350        360 
DVVATMNLNG DYISDALAAQ VGGIGIAPGA NINYVTGHAI FEATHGTAPK YAGLDKVNPS 

       370        380        390        400        410        420 
SVLLSGVLLL EHLGWNEAAK LVTASVEKTI ASKVVTYDFA RLMEGATEVK CSEFANELIK 

       430 
NMDVAIIKNA 

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References

[1]"Genome sequence of Bacillus anthracis A0248."
Dodson R.J., Munk A.C., Bruce D., Detter C., Tapia R., Sutton G., Sims D., Brettin T.
Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: A0248 EMBL ACQ49570.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001598 Genomic DNA. Translation: ACQ49570.1.
RefSeqYP_002868872.1. NC_012659.1.

3D structure databases

ProteinModelPortalC3PAI2.
SMRC3PAI2. Positions 1-423.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING592021.BAA_4849.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACQ49570; ACQ49570; BAA_4849.
GeneID7848029.
KEGGbai:BAA_4849.
PATRIC18775597. VBIBacAnt132916_5109.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0538.
HOGENOMHOG000021113.
KOK00031.
OMACLRPIRY.
OrthoDBEOG6SNDTP.

Enzyme and pathway databases

BioCycBANT592021:GJAQ-4796-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC3PAI2_BACAA
AccessionPrimary (citable) accession number: C3PAI2
Entry history
Integrated into UniProtKB/TrEMBL: June 16, 2009
Last sequence update: June 16, 2009
Last modified: May 14, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)