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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Vibrio cholerae serotype O1 (strain MJ-1236)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei140 – 1401UniRule annotation
Active sitei545 – 5451UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciVCHO593588:GI2R-762-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:VCD_001717Imported
OrganismiVibrio cholerae serotype O1 (strain MJ-1236)Imported
Taxonomic identifieri593588 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000001618: Chromosome 1

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi593588.VCD_001717.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C3NUW3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTMNEKYAAL KSNVSMLGRL LGQTIQAADG DVILAKVETI RKLSKSARAG
60 70 80 90 100
NQADRELLIE EIKNLPNHQL TPVARAFNQF LNLTNIAEQY HTISRHCESH
110 120 130 140 150
VNELDAIGSL FAKLAQKSVS KFDTAQAIRD LNIELVLTAH PTEITRRTMI
160 170 180 190 200
NKLVKINECL SKLELSDLSP KERHKTERRL EQLIAQSWHS DVIRQQRPTP
210 220 230 240 250
LDEAKWGFAV VENSLWHAVP EFLRELDEQV KSYLGEGLPI DARPVHFSSW
260 270 280 290 300
MGGDRDGNPF VTHTITREVL LLSRWKAADL YLTDINELVS ELSMTKCNEA
310 320 330 340 350
VRALAGEEHE PYRAILKPIR SLLQETIEIL DAKLNGQKLA VKAPLQTADQ
360 370 380 390 400
LWEPLYACYQ SLHECGMGVI ADGSLLDTLR RIKAFGVHLV RLDVRQESSR
410 420 430 440 450
HAEVISELTR HLGIGDYNQW SEQDKIAFLT TELNSKRPLL PRDWQPSPQV
460 470 480 490 500
KEVLDTCKII AAQSKDAFGA YVISMARTAS DVLAVHLLLQ EAGCPYRMDV
510 520 530 540 550
CPLFETLDDL NNAESVIRQL MNIDLYRGFI QNHQMVMIGY SDSAKDAGVM
560 570 580 590 600
AAGWAQYRAM EALVKVGEEA GIELTLFHGR GGTIGRGGAP AHAALLSQPP
610 620 630 640 650
KSLKGGLRVT EQGEMIRFKL GLPEVAVNSF NMYASAILEA NLLPPPEPKN
660 670 680 690 700
EWRALMDILS EISCNAYRKV VRGEPDFVPY FRQATPELEL GKLPLGSRPA
710 720 730 740 750
KRNPTGGVES LRAIPWIFSW SQNRLILPAW LGAGEAIQIA INEGHQALLE
760 770 780 790 800
EMCREWPFFS TRLGMLEMVY TKCSVSIACH YDERLVEPTL RPLGEKLRAQ
810 820 830 840 850
LQQDIKVVLN VENNENLMQS DPWGQESIRL RNIYIEPLNM LQAELLYRTR
860 870
QSELPAPELE EALMVTIAGI AAGMRNTG
Length:878
Mass (Da):98,549
Last modified:June 16, 2009 - v1
Checksum:i32A229269604CFB0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001485 Genomic DNA. Translation: ACQ59886.1.
RefSeqiYP_002877456.1. NC_012668.1.

Genome annotation databases

EnsemblBacteriaiACQ59886; ACQ59886; VCD_001717.
GeneIDi7855205.
KEGGivcj:VCD_001717.
PATRICi20074776. VBIVibCho20143_1738.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001485 Genomic DNA. Translation: ACQ59886.1.
RefSeqiYP_002877456.1. NC_012668.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi593588.VCD_001717.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACQ59886; ACQ59886; VCD_001717.
GeneIDi7855205.
KEGGivcj:VCD_001717.
PATRICi20074776. VBIVibCho20143_1738.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciVCHO593588:GI2R-762-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MJ-1236Imported.

Entry informationi

Entry nameiC3NUW3_VIBCJ
AccessioniPrimary (citable) accession number: C3NUW3
Entry historyi
Integrated into UniProtKB/TrEMBL: June 16, 2009
Last sequence update: June 16, 2009
Last modified: March 4, 2015
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.