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C3NUC8 (C3NUC8_VIBCJ) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Soluble pyridine nucleotide transhydrogenase HAMAP MF_00247
Short name=STH HAMAP MF_00247
EC=1.6.1.1 HAMAP MF_00247
Alternative name(s):
NAD(P)(+) transhydrogenase [B-specific] HAMAP MF_00247
Gene names
Name:sthA HAMAP MF_00247
Ordered Locus Names:VCD_001608
OrganismVibrio cholerae serotype O1 (strain MJ-1236) [Complete proteome] [HAMAP]
Taxonomic identifier593588 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length466 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation By similarity. HAMAP MF_00247 SAAS SAAS004099

Catalytic activity

NADPH + NAD+ = NADP+ + NADH. HAMAP MF_00247 SAAS SAAS004099

Cofactor

Binds 1 FAD per subunit By similarity. HAMAP MF_00247 SAAS SAAS004099

Subcellular location

Cytoplasm By similarity HAMAP MF_00247.

Sequence similarities

Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. HAMAP MF_00247

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding36 – 4510FAD By similarity HAMAP MF_00247

Sequences

Sequence LengthMass (Da)Tools
C3NUC8 [UniParc].

Last modified June 16, 2009. Version 1.
Checksum: 60D05DB3FD595BE1

FASTA46650,942
        10         20         30         40         50         60 
MGQKNHFDVI VIGSGPGGEG AAMGLTKGGK NVAIIEKESS VGGGCTHWGT IPSKALRHAV 

        70         80         90        100        110        120 
SRIIEFNSNP LFCKNNSSIH ATFSTILSHA KSVIDKQTRL RQGFYDRNQC TLIFGAAHFI 

       130        140        150        160        170        180 
DAHTVAVKKA DGSIDTYSAD KFVIATGSRP YHPKDVDFGH PRIYDSDSIL NLEHDPRHII 

       190        200        210        220        230        240 
IYGAGVIGCE YASIFRGLDV KTDLINTRDR LLSFLDNEVS DALSYHFWNS GVVIRNDETY 

       250        260        270        280        290        300 
DKVEGTSDGV IVHLKSGKKM RADCLLYANG RTGNTDKLNL ESVGLQADSR GQLVVNANYQ 

       310        320        330        340        350        360 
TQVEHIYAVG DVIGYPSLAS AAYDQGRFVA QAIIHGQAAH LLTEDIPTGI YTIPEISSVG 

       370        380        390        400        410        420 
RTEQELTAAK VPYEVGRASF KHLARAQIAG KDIGSLKILF HRETKEILGI HCFGERAAEI 

       430        440        450        460 
IHIGQAIMEQ KGEANTIEYF VNTTFNYPTM AEAFRVAALN GLNRLF

« Hide

References

[1]"Comparative genomics reveals mechanism for short-term and long-term clonal transitions in pandemic Vibrio cholerae."
Chun J., Grim C.J., Hasan N.A., Lee J.H., Choi S.Y., Haley B.J., Taviani E., Jeon Y.-S., Kim D.W., Lee J.-H., Brettin T.S., Bruce D.C., Challacombe J.F., Detter J.C., Han C.S., Munk A.C., Chertkov O., Meincke L. expand/collapse author list , Saunders E., Walters R.A., Huq A., Nair G.B., Colwell R.R.
Proc. Natl. Acad. Sci. U.S.A. 106:15442-15447(2009) [PubMed: 19720995] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001485 Genomic DNA. Translation: ACQ59777.1.
RefSeqYP_002877347.1. NC_012668.1.

3D structure databases

ProteinModelPortalC3NUC8.
ModBaseSearch...

Protein-protein interaction databases

STRINGC3NUC8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7857056.
GenomeReviewsGene locus VCD_001608 in contig CP001485_GR.
KEGGvcj:VCD_001608.
PATRIC20074538. VBIVibCho20143_1627.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAGEGNTIE.
ProtClustDBPRK05249.

Family and domain databases

HAMAPMF_00247. SthA.
[Tree]
InterProIPR016156. FAD/NAD-linked_Rdtase_dimer.
IPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR004099. Pyr_nucl-diS_OxRdtase_dimer.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
IPR022962. STH.
[Graphical view]
Gene3DG3DSA:3.30.390.30. Pyr_redox_dim. 1 hit.
KOK00322.
PfamPF00070. Pyr_redox. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
PF02852. Pyr_redox_dim. 1 hit.
[Graphical view]
PRINTSPR00368. FADPNR.
SUPFAMSSF55424. FAD/NAD-linked_reductase_dimer. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC3NUC8_VIBCJ
AccessionPrimary (citable) accession number: C3NUC8
Entry history
Integrated into UniProtKB/TrEMBL: June 16, 2009
Last sequence update: June 16, 2009
Last modified: December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info