C3NRR3 (C3NRR3_VIBCJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Acetate kinase 2 HAMAP MF_00020
EC=2.7.2.1 HAMAP MF_00020

Alternative name(s):
Acetokinase 2 HAMAP MF_00020

Gene names

Name:	ackA2 HAMAP MF_00020
Ordered Locus Names:	VCD_003243

Organism

Vibrio cholerae serotype O1 (strain MJ-1236) [Complete proteome] [HAMAP]

Taxonomic identifier

593588 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	398 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 SAAS SAAS000890 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020 SAAS SAAS000890
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity HAMAP MF_00020.
Sequence similarities	Belongs to the acetokinase family. HAMAP MF_00020 RuleBase RU003835

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00020 SAAS SAAS000890
Ligand	ATP-binding HAMAP MF_00020 SAAS SAAS000890 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00020 SAAS SAAS000890 RuleBase RU003835 EMBL ACQ61403.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C3NRR3 [UniParc]. Last modified June 16, 2009. Version 1. Checksum: 42D6CE78F8B410B6	FASTA	398	42,843
	10 20 30 40 50 60 MSKLVLVLNC GSSSLKFAVV DAQSGEQHLS GLAECLHLPE ARIKWKLDGK HEAQLGEGAA 70 80 90 100 110 120 HDEALSFIVE TILASKPELA AQLKAIGHRV VHGGEQFTQS ALIDDAVLKG IEDCAALAPL 130 140 150 160 170 180 HNPAHIIGIK AAQKAFPELK NVAVFDTAFH QTMPEEAYLY ALPYNLYKEH GIRRYGMHGT 190 200 210 220 230 240 SHLFIAREAA ERLGKPANEL NIINCHLGNG ASVCAIKNGQ SVDTSMGLTP LEGLVMGTRC 250 260 270 280 290 300 GDIDPAIIFH LHDTLGYSVE KINTMLTKES GLLGLTEVTS DCRFVEDNYG QKEEATRAMD 310 320 330 340 350 360 VFCHRLAKYV AGYTASLDGR LDAITFTGGI GENSAPIREM VLNRLAIFGI TVDSAANLKA 370 380 390 RFGGEGVITT ADSRIPAMVI ATNEELVIAE DTARLTNI

References

[1]

"Comparative genomics reveals mechanism for short-term and long-term clonal transitions in pandemic Vibrio cholerae." Chun J., Grim C.J., Hasan N.A., Lee J.H., Choi S.Y., Haley B.J., Taviani E., Jeon Y.-S., Kim D.W., Lee J.-H., Brettin T.S., Bruce D.C., Challacombe J.F., Detter J.C., Han C.S., Munk A.C., Chertkov O., Meincke L. , Saunders E., Walters R.A., Huq A., Nair G.B., Colwell R.R. Proc. Natl. Acad. Sci. U.S.A. 106:15442-15447(2009) [PubMed: 19720995] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001485 Genomic DNA. Translation: ACQ61403.1.
RefSeq	YP_002878973.1. NC_012668.1.
3D structure databases
ProteinModelPortal	C3NRR3.
ModBase	Search...
Protein-protein interaction databases
STRING	C3NRR3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7854833.
GenomeReviews	Gene locus VCD_003243 in contig CP001485_GR.
KEGG	vcj:VCD_003243.
PATRIC	20077887. VBIVibCho20143_3256.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	YLPEARI.
ProtClustDB	PRK00180.
Family and domain databases
HAMAP	MF_00020. Acetate_kinase. [Tree]
InterPro	IPR004372. Ac/Proprionate_kinase. IPR000890. Aliphatic_acid_kin_short-chain. IPR023865. Aliphatic_acid_kinase_CS. [Graphical view]
KO	K00925.
PANTHER	PTHR21060. Acetate_kin. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. AckA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C3NRR3_VIBCJ

Accession

Primary (citable) accession number: C3NRR3

Entry history

Integrated into UniProtKB/TrEMBL:	June 16, 2009
Last sequence update:	June 16, 2009
Last modified:	December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)