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C3NRN6

- C3NRN6_VIBCJ

UniProt

C3NRN6 - C3NRN6_VIBCJ

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Protein

Adenylosuccinate lyase

Gene

VCD_003216

Organism
Vibrio cholerae serotype O1 (strain MJ-1236)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.UniRule annotation
N(6)-(1,2-dicarboxyethyl)AMP = fumarate + AMP.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity Source: UniProtKB-EC
  2. N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity Source: UniProtKB-EC

GO - Biological processi

  1. 'de novo' AMP biosynthetic process Source: UniProtKB-UniPathway
  2. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported

Keywords - Biological processi

Purine biosynthesisUniRule annotation

Enzyme and pathway databases

BioCyciVCHO593588:GI2R-2290-MONOMER.
UniPathwayiUPA00074; UER00132.
UPA00075; UER00336.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenylosuccinate lyaseUniRule annotation (EC:4.3.2.2UniRule annotation)
Short name:
ASLUniRule annotation
Alternative name(s):
AdenylosuccinaseUniRule annotation
Gene namesi
Ordered Locus Names:VCD_003216Imported
OrganismiVibrio cholerae serotype O1 (strain MJ-1236)Imported
Taxonomic identifieri593588 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000001618: Chromosome 1

Interactioni

Protein-protein interaction databases

STRINGi593588.VCD_003216.

Structurei

3D structure databases

ProteinModelPortaliC3NRN6.
SMRiC3NRN6. Positions 1-456.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0015.
HOGENOMiHOG000252916.
KOiK01756.
OMAiPANYIGN.
OrthoDBiEOG686NDB.

Family and domain databases

Gene3Di1.10.275.10. 1 hit.
InterProiIPR024083. Fumarase/histidase_N.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
IPR004769. Pur_lyase.
IPR013539. PurB_C.
[Graphical view]
PANTHERiPTHR11444. PTHR11444. 1 hit.
PfamiPF08328. ASL_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view]
PRINTSiPR00149. FUMRATELYASE.
SUPFAMiSSF48557. SSF48557. 1 hit.
TIGRFAMsiTIGR00928. purB. 1 hit.
PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C3NRN6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MELSALTAVS PVDGRYGSKT IALRSIFSEF GLLKYRTIVE IRWLQKLAAT
60 70 80 90 100
AEIAEVPAFS AEANQFLDAI AANFNEADAL RIKEIERTTN HDVKAVEYFL
110 120 130 140 150
KEKVAAMPEL HAVNEFIHFA CTSEDINNTS HALMLKEARD TVILPEIRNV
160 170 180 190 200
IDAIRKLAEE YRDIPLLSRT HGQPASPSTM GKEMANVAYR MERQYKQIAN
210 220 230 240 250
VEILAKINGA VGNYNAHLSA YPTVDWHKFS EEFITESLGV DWNPYTTQIE
260 270 280 290 300
PHDYIAELFE AVARFNTILI DFDRDVWGYI ALGHFKQRTI AGEIGSSTMP
310 320 330 340 350
HKVNPIDFEN SEGNLGLANA VFTHLAQKLP ISRWQRDLTD STVLRNLGVG
360 370 380 390 400
VGYAIIAYTS TLKGISKLEV NRDALLAELD HNWEVLAEPI QTVMRRYGIE
410 420 430 440 450
KPYEKLKELT RGKRVDGEAM RQFIDGLALP AEEKTRLKAM TPASYIGYAI

ELTDKL
Length:456
Mass (Da):51,335
Last modified:June 16, 2009 - v1
Checksum:i1B57F9A5A1FDD859
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001485 Genomic DNA. Translation: ACQ61376.1.
RefSeqiYP_002878946.1. NC_012668.1.

Genome annotation databases

EnsemblBacteriaiACQ61376; ACQ61376; VCD_003216.
GeneIDi7854806.
KEGGivcj:VCD_003216.
PATRICi20077833. VBIVibCho20143_3229.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001485 Genomic DNA. Translation: ACQ61376.1 .
RefSeqi YP_002878946.1. NC_012668.1.

3D structure databases

ProteinModelPortali C3NRN6.
SMRi C3NRN6. Positions 1-456.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 593588.VCD_003216.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACQ61376 ; ACQ61376 ; VCD_003216 .
GeneIDi 7854806.
KEGGi vcj:VCD_003216.
PATRICi 20077833. VBIVibCho20143_3229.

Phylogenomic databases

eggNOGi COG0015.
HOGENOMi HOG000252916.
KOi K01756.
OMAi PANYIGN.
OrthoDBi EOG686NDB.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00132 .
UPA00075 ; UER00336 .
BioCyci VCHO593588:GI2R-2290-MONOMER.

Family and domain databases

Gene3Di 1.10.275.10. 1 hit.
InterProi IPR024083. Fumarase/histidase_N.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
IPR004769. Pur_lyase.
IPR013539. PurB_C.
[Graphical view ]
PANTHERi PTHR11444. PTHR11444. 1 hit.
Pfami PF08328. ASL_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view ]
PRINTSi PR00149. FUMRATELYASE.
SUPFAMi SSF48557. SSF48557. 1 hit.
TIGRFAMsi TIGR00928. purB. 1 hit.
PROSITEi PS00163. FUMARATE_LYASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MJ-1236Imported.

Entry informationi

Entry nameiC3NRN6_VIBCJ
AccessioniPrimary (citable) accession number: C3NRN6
Entry historyi
Integrated into UniProtKB/TrEMBL: June 16, 2009
Last sequence update: June 16, 2009
Last modified: October 29, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3