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C3NR58 (C3NR58_VIBCJ) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Succinylglutamate desuccinylase HAMAP-Rule MF_00767

EC=3.5.1.96 HAMAP-Rule MF_00767
Gene names
Name:astE HAMAP-Rule MF_00767
Ordered Locus Names:VCD_003107 EMBL ACQ61267.1
OrganismVibrio cholerae serotype O1 (strain MJ-1236) [Complete proteome] [HAMAP] EMBL ACQ61267.1
Taxonomic identifier593588 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Protein attributes

Sequence length342 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Transforms N(2)-succinylglutamate into succinate and glutamate By similarity. HAMAP-Rule MF_00767 SAAS SAAS016681

Catalytic activity

N-succinyl-L-glutamate + H2O = succinate + L-glutamate. HAMAP-Rule MF_00767 SAAS SAAS016681

Cofactor

Binds 1 zinc ion per subunit By similarity. HAMAP-Rule MF_00767 SAAS SAAS016681

Pathway

Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 5/5. HAMAP-Rule MF_00767 SAAS SAAS016681

Sequence similarities

Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily. HAMAP-Rule MF_00767

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2191 By similarity HAMAP-Rule MF_00767
Metal binding631Zinc By similarity HAMAP-Rule MF_00767
Metal binding661Zinc By similarity HAMAP-Rule MF_00767
Metal binding1551Zinc By similarity HAMAP-Rule MF_00767

Sequences

Sequence LengthMass (Da)Tools
C3NR58 [UniParc].

Last modified June 16, 2009. Version 1.
Checksum: D5D646FA0F6E3796

FASTA34239,093
        10         20         30         40         50         60 
MTKSLFRQSF LFDSLDLDHP MVAQTVRTEQ GVTLKLHQRG VLEVIPAQTD AATKNMVISC 

        70         80         90        100        110        120 
GIHGDETAPM ELLDKWIDDI VSGFQPVAER CLFIMAHPQA TVRHVRFIEQ NLNRLFDDKP 

       130        140        150        160        170        180 
HTPSTELAIA DNLKVLLRQF FANTDEHSRW HLDLHCAIRG SKHYSFAVSP KARHPVRSRS 

       190        200        210        220        230        240 
LMQFIEQAHI EAVMLSNAPS STFSWYSAEH YAAQALTLEL GQVARLGENL LDRLLAFDLA 

       250        260        270        280        290        300 
MRDLISRHKP EHLPRKSVMY RVSRTIVRLH DDFDFRFSDD VENFTAFMHG EVFGHDGDKP 

       310        320        330        340 
LMAKNEGEAI VFPNRKVAIG QRAALMVCKV NTRYEDDQLV YD 

« Hide

References

[1]"Comparative genomics reveals mechanism for short-term and long-term clonal transitions in pandemic Vibrio cholerae."
Chun J., Grim C.J., Hasan N.A., Lee J.H., Choi S.Y., Haley B.J., Taviani E., Jeon Y.-S., Kim D.W., Lee J.-H., Brettin T.S., Bruce D.C., Challacombe J.F., Detter J.C., Han C.S., Munk A.C., Chertkov O., Meincke L. expand/collapse author list , Saunders E., Walters R.A., Huq A., Nair G.B., Colwell R.R.
Proc. Natl. Acad. Sci. U.S.A. 106:15442-15447(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MJ-1236.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001485 Genomic DNA. Translation: ACQ61267.1.
RefSeqYP_002878837.1. NC_012668.1.

3D structure databases

ProteinModelPortalC3NR58.
SMRC3NR58. Positions 3-342.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING593588.VCD_003107.

Proteomic databases

PRIDEC3NR58.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACQ61267; ACQ61267; VCD_003107.
GeneID7857345.
KEGGvcj:VCD_003107.
PATRIC20077611. VBIVibCho20143_3122.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2988.
HOGENOMHOG000280300.
KOK05526.
OMATAPIEIC.
OrthoDBEOG613070.

Enzyme and pathway databases

BioCycVCHO593588:GI2R-2177-MONOMER.
UniPathwayUPA00185; UER00283.

Family and domain databases

HAMAPMF_00767. Arg_catab_AstE.
InterProIPR007036. Aste_AspA.
IPR016681. SuccinylGlu_desuccinylase.
[Graphical view]
PfamPF04952. AstE_AspA. 1 hit.
[Graphical view]
PIRSFPIRSF017020. AstE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC3NR58_VIBCJ
AccessionPrimary (citable) accession number: C3NR58
Entry history
Integrated into UniProtKB/TrEMBL: June 16, 2009
Last sequence update: June 16, 2009
Last modified: June 11, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)