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C3NNU1

- C3NNU1_VIBCJ

UniProt

C3NNU1 - C3NNU1_VIBCJ

Protein

Succinyl-CoA ligase [ADP-forming] subunit alpha

Gene

VCD_002283

Organism
Vibrio cholerae serotype O1 (strain MJ-1236)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (16 Jun 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + succinate + CoA = ADP + phosphate + succinyl-CoA.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei247 – 2471Tele-phosphohistidine intermediateUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. ATP citrate synthase activity Source: InterPro
    3. cofactor binding Source: InterPro
    4. succinate-CoA ligase (ADP-forming) activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    LigaseUniRule annotationImported

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciVCHO593588:GI2R-1352-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Succinyl-CoA ligase [ADP-forming] subunit alphaUniRule annotation (EC:6.2.1.5UniRule annotation)
    Gene namesi
    Ordered Locus Names:VCD_002283Imported
    OrganismiVibrio cholerae serotype O1 (strain MJ-1236)Imported
    Taxonomic identifieri593588 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
    ProteomesiUP000001618: Chromosome 1

    Interactioni

    Subunit structurei

    Heterotetramer of two alpha and two beta subunits.UniRule annotation
    Heterotetramer of two alpha and two beta subunits By similarity.

    Protein-protein interaction databases

    STRINGi593588.VCD_002283.

    Structurei

    3D structure databases

    ProteinModelPortaliC3NNU1.
    SMRiC3NNU1. Positions 2-287.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the succinate/malate CoA ligase alpha subunit family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0074.
    HOGENOMiHOG000239685.
    KOiK01902.
    OMAiFEQDPQT.
    OrthoDBiEOG644ZT0.

    Family and domain databases

    Gene3Di3.40.50.261. 1 hit.
    3.40.50.720. 1 hit.
    InterProiIPR017440. Cit_synth/succinyl-CoA_lig_AS.
    IPR003781. CoA-bd.
    IPR005810. CoA_lig_alpha.
    IPR005811. CoA_ligase.
    IPR016040. NAD(P)-bd_dom.
    IPR016102. Succinyl-CoA_synth-like.
    [Graphical view]
    PfamiPF02629. CoA_binding. 1 hit.
    PF00549. Ligase_CoA. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001553. SucCS_alpha. 1 hit.
    PRINTSiPR01798. SCOASYNTHASE.
    SMARTiSM00881. CoA_binding. 1 hit.
    [Graphical view]
    SUPFAMiSSF52210. SSF52210. 1 hit.
    TIGRFAMsiTIGR01019. sucCoAalpha. 1 hit.
    PROSITEiPS01216. SUCCINYL_COA_LIG_1. 1 hit.
    PS00399. SUCCINYL_COA_LIG_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C3NNU1-1 [UniParc]FASTAAdd to Basket

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    MSILINKDTK VICQGFTGGQ GTFHSEQAIA YGTQMVGGVS PGKGGTTHLG    50
    LPVFNTVREA VEVTGATATV IYVPAPFCKD AILEAIDAGI KLIVTITEGI 100
    PTTDMIDVKV KLEQTGVRMI GPNCPGVITP DECKIGIMPG HIHKKGKVGI 150
    VSRSGTLTYE AVKQTTDEGF GQSTCVGIGG DPIPGSNFID ILKMFQEDPA 200
    TEAIVMIGEI GGTAEEEAAA FIKANVTKPV VSYIAGVTAP PGKRMGHAGA 250
    IISGGKGTAE EKFAALESAG VKTVKSLADI GKALREVTGW 290
    Length:290
    Mass (Da):29,941
    Last modified:June 16, 2009 - v1
    Checksum:i7573EBE60C271086
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001485 Genomic DNA. Translation: ACQ60450.1.
    RefSeqiYP_002878020.1. NC_012668.1.

    Genome annotation databases

    EnsemblBacteriaiACQ60450; ACQ60450; VCD_002283.
    GeneIDi7856077.
    KEGGivcj:VCD_002283.
    PATRICi20075969. VBIVibCho20143_2309.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001485 Genomic DNA. Translation: ACQ60450.1 .
    RefSeqi YP_002878020.1. NC_012668.1.

    3D structure databases

    ProteinModelPortali C3NNU1.
    SMRi C3NNU1. Positions 2-287.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 593588.VCD_002283.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACQ60450 ; ACQ60450 ; VCD_002283 .
    GeneIDi 7856077.
    KEGGi vcj:VCD_002283.
    PATRICi 20075969. VBIVibCho20143_2309.

    Phylogenomic databases

    eggNOGi COG0074.
    HOGENOMi HOG000239685.
    KOi K01902.
    OMAi FEQDPQT.
    OrthoDBi EOG644ZT0.

    Enzyme and pathway databases

    BioCyci VCHO593588:GI2R-1352-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.261. 1 hit.
    3.40.50.720. 1 hit.
    InterProi IPR017440. Cit_synth/succinyl-CoA_lig_AS.
    IPR003781. CoA-bd.
    IPR005810. CoA_lig_alpha.
    IPR005811. CoA_ligase.
    IPR016040. NAD(P)-bd_dom.
    IPR016102. Succinyl-CoA_synth-like.
    [Graphical view ]
    Pfami PF02629. CoA_binding. 1 hit.
    PF00549. Ligase_CoA. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001553. SucCS_alpha. 1 hit.
    PRINTSi PR01798. SCOASYNTHASE.
    SMARTi SM00881. CoA_binding. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52210. SSF52210. 1 hit.
    TIGRFAMsi TIGR01019. sucCoAalpha. 1 hit.
    PROSITEi PS01216. SUCCINYL_COA_LIG_1. 1 hit.
    PS00399. SUCCINYL_COA_LIG_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MJ-1236Imported.

    Entry informationi

    Entry nameiC3NNU1_VIBCJ
    AccessioniPrimary (citable) accession number: C3NNU1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 16, 2009
    Last sequence update: June 16, 2009
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3