C3NJZ2 (UPPP_SULIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Undecaprenyl-diphosphatase
EC=3.6.1.27

Alternative name(s):
Undecaprenyl pyrophosphate phosphatase

Gene names

Name:	uppP
Ordered Locus Names:	YN1551_0205

Organism

Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2) [Complete proteome] [HAMAP]

Taxonomic identifier

419942 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus › Sulfolobus islandicus

Protein attributes

Sequence length	265 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) By similarity. HAMAP-Rule MF_01006
Catalytic activity	Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006
Subcellular location	Cell membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.
Sequence similarities	Belongs to the UppP family.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dephosphorylation Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	undecaprenyl-diphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 265	265	Undecaprenyl-diphosphatase HAMAP-Rule MF_01006		PRO_1000213159
Regions
	Transmembrane	41 – 61	21	Helical; Potential
	Transmembrane	75 – 95	21	Helical; Potential
	Transmembrane	104 – 124	21	Helical; Potential
	Transmembrane	137 – 157	21	Helical; Potential
	Transmembrane	180 – 200	21	Helical; Potential
	Transmembrane	215 – 235	21	Helical; Potential
	Transmembrane	244 – 264	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	C3NJZ2 [UniParc]. Last modified June 16, 2009. Version 1. Checksum: 98FA8C2616435B10	FASTA	265	28,780
	10 20 30 40 50 60 MNFLVSILLG IIQGISEWLP ISSKTQELIA SHYLLGLDVS IAYTFGLFME MGSIGSALIY 70 80 90 100 110 120 FRQDVKRVFH DKFLLKFLVV VTALTGIVGV PLYVISDKLL QNAYNPSIPM IFLGIALIAD 130 140 150 160 170 180 GIYIRYSRSR TREFKNLSTK EMILIGIAQG IAALPGVSRS GMTVSTMLVL GINPEDAFHY 190 200 210 220 230 240 SYLAYIPAAI GSVGTTLLFT RHHISYVVSL IGIDGIALAV ISALLTGLVV IGFLLKIAKT 250 260 KKVYLIDFML GGIAVLVSML GLIIS

References

[1]	"Biogeography of the Sulfolobus islandicus pan-genome." Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J. Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Y.N.15.51 / Yellowstone #2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001404 Genomic DNA. Translation: ACP47394.1.
RefSeq	YP_002839316.1. NC_012623.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	419942.YN1551_0205.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACP47394; ACP47394; YN1551_0205.
GeneID	7808743.
KEGG	sin:YN1551_0205.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1968.
HOGENOM	HOG000218357.
KO	K06153.
OMA	NDWLDKH.
ProtClustDB	PRK00281.
Enzyme and pathway databases
BioCyc	SISL419942:GHVO-260-MONOMER.
Family and domain databases
HAMAP	MF_01006. Undec_diphosphatase.
InterPro	IPR003824. Bacitracin-R_BacA. [Graphical view]
Pfam	PF02673. BacA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UPPP_SULIN

Accession

Primary (citable) accession number: C3NJZ2

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	June 16, 2009
Last modified:	May 1, 2013
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program