C3NG02 (AROC_SULIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Chorismate synthase
EC=4.2.3.5

Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase

Gene names

Name:	aroC
Ordered Locus Names:	YN1551_1013

Organism

Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2) [Complete proteome] [HAMAP]

Taxonomic identifier

419942 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus

Protein attributes

Sequence length	391 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300
Cofactor	Reduced flavin By similarity. HAMAP MF_00300
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300
Sequence similarities	Belongs to the chorismate synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	chorismate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 391	391	Chorismate synthase HAMAP MF_00300		PRO_1000204963

Sequences

	Sequence		Length	Mass (Da)
	C3NG02 [UniParc]. Last modified June 16, 2009. Version 1. Checksum: 45BC3807D37E642A	FASTA	391	43,243
	10 20 30 40 50 60 MPGNSFGKLF RVTTFGESHG PAVGVVIDGV PAGLPLTVED IKFELEFRKP GRLYVSGRRE 70 80 90 100 110 120 KDEPEILSGI FNNRTTGSPI AVIVRNTDVI SSFYEEIRYK PRPGHADLPF IMKYGYENWD 130 140 150 160 170 180 YRGGGRASAR ETVGRVIAGA VAKKLLMLAD TWIAGHLRSL GPEELNEEVT FEEVLCSKYS 190 200 210 220 230 240 PVRASKKVLE EKYEALIKKA TQEGDSYGGI AEVITKNPPI GLGEPVFDKM KAELAKAIMS 250 260 270 280 290 300 IPAVTGFEYG LGFMVSKMKG SEANDEIIRK DNKIGWKYNY AGGILGGLTN GEDLIVRCAF 310 320 330 340 350 360 KPTSSIRKPQ KTIDLRNLEE TYISVIGRHD PAVAIRGVTV VESMVALTLV DHAMRAGVIP 370 380 390 LVKLTEEQGN IVQQRWERYV RSCKPMEESQ L

References

[1]	"Biogeography of the Sulfolobus islandicus pan-genome." Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J. Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009) [PubMed: 19435847] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Y.N.15.51 / Yellowstone #2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001404 Genomic DNA. Translation: ACP48120.1.
RefSeq	YP_002840042.1. NC_012623.1.
3D structure databases
ProteinModelPortal	C3NG02.
ModBase	Search...
Protein-protein interaction databases
STRING	C3NG02.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7809625.
GenomeReviews	Gene locus YN1551_1013 in contig CP001404_GR.
KEGG	sin:YN1551_1013.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	SRFTTQR.
ProtClustDB	PRK05382.
Family and domain databases
HAMAP	MF_00300. Chorismate_synth. [Tree]
InterPro	IPR000453. Chorismate_synth. IPR020541. Chorismate_synthase_CS. [Graphical view]
KO	K01736.
PANTHER	PTHR21085. Chorismate_synth. 1 hit.
Pfam	PF01264. Chorismate_synt. 1 hit. [Graphical view]
PIRSF	PIRSF001456. Chorismate_synth. 1 hit.
SUPFAM	SSF103263. Chorismate_synth. 1 hit.
TIGRFAMs	TIGR00033. AroC. 1 hit.
PROSITE	PS00787. CHORISMATE_SYNTHASE_1. 1 hit. PS00788. CHORISMATE_SYNTHASE_2. 1 hit. PS00789. CHORISMATE_SYNTHASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROC_SULIN

Accession

Primary (citable) accession number: C3NG02

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	June 16, 2009
Last modified:	November 16, 2011
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program