C3NEH0 (KCY_SULIY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytidylate kinase
Short name=CK
EC=2.7.4.25

Alternative name(s):
Cytidine monophosphate kinase
Short name=CMP kinase

Gene names

Name:	cmk
Ordered Locus Names:	YG5714_1442

Organism

Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1) [Complete proteome] [HAMAP]

Taxonomic identifier

439386 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus

Protein attributes

Sequence length	189 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00239
Subcellular location	Cytoplasm By similarity HAMAP MF_00239.
Sequence similarities	Belongs to the cytidylate kinase family. Type 2 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cytidylate kinase activity Inferred from electronic annotation. Source: InterPro shikimate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 189	189	Cytidylate kinase HAMAP MF_00239		PRO_1000204464
Regions
	Nucleotide binding	7 – 15	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	C3NEH0 [UniParc]. Last modified June 16, 2009. Version 1. Checksum: 9EB1BE5205D8A3E6	FASTA	189	21,730
	10 20 30 40 50 60 MIIIISGPPG SGKTSVAIKL ANELSYKFIS AGKIFRDIAQ KMGLDIINLN KVAESNFDID 70 80 90 100 110 120 KMVDKKIFEF ILSEKNLIIE SHIAGWLFRE YTNIAIYLWA PLKIRANRIA IRDKISYDQA 130 140 150 160 170 180 ISQIIKREYM HYKRFNKFYG IDINDLSVFD LVINTSNVDV NNIVKLILTY LSLVSQNPQP LKEKDINDK

References

[1]	"Biogeography of the Sulfolobus islandicus pan-genome." Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J. Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009) [PubMed: 19435847] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Y.G.57.14 / Yellowstone #1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001403 Genomic DNA. Translation: ACP45709.1.
RefSeq	YP_002837631.1. NC_012622.1.
3D structure databases
ProteinModelPortal	C3NEH0.
ModBase	Search...
Protein-protein interaction databases
STRING	C3NEH0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7806029.
GenomeReviews	Gene locus YG5714_1442 in contig CP001403_GR.
KEGG	siy:YG5714_1442.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	CAGFIFR.
ProtClustDB	PRK04182.
Family and domain databases
HAMAP	MF_00239. Cytidyl_kinase_type2. [Tree]
InterPro	IPR011892. Cyt_kin_arch. IPR000623. Shikimate_kinase. [Graphical view]
KO	K00945.
Pfam	PF01202. SKI. 1 hit. [Graphical view]
TIGRFAMs	TIGR02173. Cyt_kin_arch. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_SULIY

Accession

Primary (citable) accession number: C3NEH0

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	June 16, 2009
Last modified:	January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program