Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

C3NAL6

- PCP_SULIY

UniProt

C3NAL6 - PCP_SULIY

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Pyrrolidone-carboxylate peptidase

Gene

pcp

Organism
Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Removes 5-oxoproline from various penultimate amino acid residues except L-proline.UniRule annotation

Catalytic activityi

Release of an N-terminal pyroglutamyl group from a polypeptide, the second amino acid generally not being Pro.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei79 – 791UniRule annotation
Active sitei142 – 1421UniRule annotation
Active sitei164 – 1641UniRule annotation

GO - Molecular functioni

  1. cysteine-type peptidase activity Source: UniProtKB-KW
  2. pyroglutamyl-peptidase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Thiol protease

Enzyme and pathway databases

BioCyciSISL439386:GHF0-502-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Pyrrolidone-carboxylate peptidaseUniRule annotation (EC:3.4.19.3UniRule annotation)
Alternative name(s):
5-oxoprolyl-peptidaseUniRule annotation
Pyroglutamyl-peptidase IUniRule annotation
Short name:
PGP-IUniRule annotation
Short name:
PyraseUniRule annotation
Gene namesi
Name:pcpUniRule annotation
Ordered Locus Names:YG5714_0482
OrganismiSulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1)
Taxonomic identifieri439386 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
ProteomesiUP000002308: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytosol Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 209209Pyrrolidone-carboxylate peptidasePRO_1000206028Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase C15 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2039.
HOGENOMiHOG000242641.
KOiK01304.
OMAiERIAINC.

Family and domain databases

Gene3Di3.40.630.20. 1 hit.
HAMAPiMF_00417. Pyrrolid_peptidase.
InterProiIPR000816. Peptidase_C15.
IPR016125. Peptidase_C15-like.
IPR029762. PGP-I_bact-type.
[Graphical view]
PANTHERiPTHR23402. PTHR23402. 1 hit.
PfamiPF01470. Peptidase_C15. 1 hit.
[Graphical view]
PIRSFiPIRSF015592. Prld-crbxl_pptds. 1 hit.
PRINTSiPR00706. PYROGLUPTASE.
PROSITEiPS01334. PYRASE_CYS. 1 hit.
PS01333. PYRASE_GLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C3NAL6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTVLLFGFEP FLEYKENPSQ LIAEALNGST ILKEEVKGVI LPVEYEKIED
60 70 80 90 100
LIVTKIREMK PILTLGIGVA PGRAKITPEK IAINYKYSRE GDNAGKKYKG
110 120 130 140 150
EKIDPLGQDG IFTNIPVEDL VDLLNENGIP AELSLSAGSY LCNNAMYIII
160 170 180 190 200
REARKYNSLG GFIHVPLHES YAARIQRPIP SMSLDTMIRG IRLSMEFILT

NKKENLTFS
Length:209
Mass (Da):23,376
Last modified:June 16, 2009 - v1
Checksum:iAAFD1D3347DF3CB0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001403 Genomic DNA. Translation: ACP44776.1.
RefSeqiWP_012715634.1. NC_012622.1.
YP_002836698.1. NC_012622.1.

Genome annotation databases

EnsemblBacteriaiACP44776; ACP44776; YG5714_0482.
GeneIDi7806165.
KEGGisiy:YG5714_0482.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001403 Genomic DNA. Translation: ACP44776.1 .
RefSeqi WP_012715634.1. NC_012622.1.
YP_002836698.1. NC_012622.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACP44776 ; ACP44776 ; YG5714_0482 .
GeneIDi 7806165.
KEGGi siy:YG5714_0482.

Phylogenomic databases

eggNOGi COG2039.
HOGENOMi HOG000242641.
KOi K01304.
OMAi ERIAINC.

Enzyme and pathway databases

BioCyci SISL439386:GHF0-502-MONOMER.

Family and domain databases

Gene3Di 3.40.630.20. 1 hit.
HAMAPi MF_00417. Pyrrolid_peptidase.
InterProi IPR000816. Peptidase_C15.
IPR016125. Peptidase_C15-like.
IPR029762. PGP-I_bact-type.
[Graphical view ]
PANTHERi PTHR23402. PTHR23402. 1 hit.
Pfami PF01470. Peptidase_C15. 1 hit.
[Graphical view ]
PIRSFi PIRSF015592. Prld-crbxl_pptds. 1 hit.
PRINTSi PR00706. PYROGLUPTASE.
PROSITEi PS01334. PYRASE_CYS. 1 hit.
PS01333. PYRASE_GLU. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Y.G.57.14 / Yellowstone #1.

Entry informationi

Entry nameiPCP_SULIY
AccessioniPrimary (citable) accession number: C3NAL6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: June 16, 2009
Last modified: November 26, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3