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C3N8C3 (CAPPA_SULIY) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase

Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppcA
Ordered Locus Names:YG5714_0069
OrganismSulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1) [Complete proteome] [HAMAP]
Taxonomic identifier439386 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus

Protein attributes

Sequence length511 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_01904

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_01904

Cofactor

Magnesium By similarity. HAMAP-Rule MF_01904

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_01904

Sequence similarities

Belongs to the PEPCase type 2 family.

Ontologies

Keywords
   Biological processCarbon dioxide fixation
   LigandMagnesium
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbon fixation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

oxaloacetate metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

phosphoenolpyruvate carboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 511511Phosphoenolpyruvate carboxylase HAMAP-Rule MF_01904
PRO_1000216176

Sequences

Sequence LengthMass (Da)Tools
C3N8C3 [UniParc].

Last modified June 16, 2009. Version 1.
Checksum: EFA8F67841351C75

FASTA51158,749
        10         20         30         40         50         60 
MRIIPRTMST QHPDNAKVPE WAKSEVIEGE DEVKEAFLAY SMYGVHEVMW DAEGKDVDTH 

        70         80         90        100        110        120 
VVRKLLSNYP DYFREHILGK DVFLTYRLPN PKVEGADRKV FAETMESIPI TYDLAEKFYG 

       130        140        150        160        170        180 
NGITVPVFEV ILPMTTSNLE IISVARYYEK AVANEDELEL YDGVKVKDLV GEIYPKVIEV 

       190        200        210        220        230        240 
IPLVEDRDSL QNIDNIVEGY YKVIKPKYMR VFLARSDPAM NYGMITAVLS VKIALSELYK 

       250        260        270        280        290        300 
LSESLNFEIY PIIGVGSLPF RGHLSPENYE KVLEEYKGVY TYTIQSAFKY DYDYDKVKSA 

       310        320        330        340        350        360 
ISSINNSRIG PAKILEKYEE DVLRKITILY TERYQPIIES LANAINDVSV LLPRRRARKL 

       370        380        390        400        410        420 
HIGLFGYSRS AGKVSLPRAI SFVGSLYSIG IPPELIGISS LSNLDEKEWD IFKQNYVNFK 

       430        440        450        460        470        480 
HDLQTAARFF NWESFELIKD IWKISEDTIA KIKEDIDYAE SVIGIKLGGI DYDSRKHILM 

       490        500        510 
SSLFLLSFKE KILQESKKYL YEMALIRRSL G 

« Hide

References

[1]"Biogeography of the Sulfolobus islandicus pan-genome."
Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.
Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Y.G.57.14 / Yellowstone #1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001403 Genomic DNA. Translation: ACP44363.1.
RefSeqYP_002836285.1. NC_012622.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING439386.YG5714_0069.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACP44363; ACP44363; YG5714_0069.
GeneID7805966.
KEGGsiy:YG5714_0069.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1892.
HOGENOMHOG000038601.
KOK01595.
OMAPRAIKFT.
ProtClustDBPRK13655.

Enzyme and pathway databases

BioCycSISL439386:GHF0-69-MONOMER.

Family and domain databases

HAMAPMF_01904. PEPcase_type2.
InterProIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFPIRSF006677. UCP006677. 1 hit.
SUPFAMSSF51621. SSF51621. 1 hit.
TIGRFAMsTIGR02751. PEPCase_arch. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCAPPA_SULIY
AccessionPrimary (citable) accession number: C3N8C3
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: June 16, 2009
Last modified: February 19, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families