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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Sulfolobus islandicus (strain M.16.27)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
Biological processCarbon dioxide fixation
LigandMagnesium

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
Ordered Locus Names:M1627_0069
OrganismiSulfolobus islandicus (strain M.16.27)
Taxonomic identifieri427318 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
Proteomesi
  • UP000002307 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002161711 – 511Phosphoenolpyruvate carboxylaseAdd BLAST511

Proteomic databases

PRIDEiC3N0D7

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000038601
KOiK01595
OMAiPAMNYGL
OrthoDBiPOG093Z01LI

Family and domain databases

HAMAPiMF_01904 PEPcase_type2, 1 hit
InterProiView protein in InterPro
IPR007566 PEP_COase_arc-type
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PfamiView protein in Pfam
PF14010 PEPcase_2, 1 hit
PIRSFiPIRSF006677 UCP006677, 1 hit
SUPFAMiSSF51621 SSF51621, 1 hit
TIGRFAMsiTIGR02751 PEPCase_arch, 1 hit

Sequencei

Sequence statusi: Complete.

C3N0D7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIIPRTMST QHPDNAKVPE WAKSEVIEGE DEVKEAFLAY SMYGVHEVMW
60 70 80 90 100
DAEGKDVDTH VVRKLLSNYP DYFREHILGK DVFLTYRLPN PKVEGADRKV
110 120 130 140 150
FAETMESIPI TYDLAEKFYG NGITVPVFEV ILPMTTSNLE IISVARYYEK
160 170 180 190 200
AVANEDELEL YNGVKVKDLV GEIYPKVIEV IPLVEDRDSL QNIDNIVEGY
210 220 230 240 250
YKVIKPKYMR VFLARSDPAM NYGMITAVLS VKIALSELYK LSESLNFEIY
260 270 280 290 300
PIIGVGSLPF RGHLSPENYE KVLEEYKGVY TYTIQSAFKY DYDYDKVKSA
310 320 330 340 350
ISSINNSRIG PAKILEKYEE DVLRKITILY TERYQPIIES LANAINDVSV
360 370 380 390 400
LLPRRRARKL HIGLFGYSRS AGKVSLPRAI SFVGSLYSIG IPPELIGISS
410 420 430 440 450
LSNLDEKEWD IFKQNYVNFK HDLQTAARFF NWESFELIKD IWKISEDTIA
460 470 480 490 500
KIKEDIDYAE SVIGIKLGDI DYDSRKHILM SSLFLLSFKE KILQESKKYL
510
YEMALIRRSL G
Length:511
Mass (Da):58,806
Last modified:June 16, 2009 - v1
Checksum:i63438D39932AF2D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001401 Genomic DNA Translation: ACP54098.1
RefSeqiWP_012710248.1, NC_012632.1

Genome annotation databases

EnsemblBacteriaiACP54098; ACP54098; M1627_0069
GeneIDi7813679
KEGGisim:M1627_0069

Similar proteinsi

Entry informationi

Entry nameiCAPPA_SULIA
AccessioniPrimary (citable) accession number: C3N0D7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: June 16, 2009
Last modified: May 23, 2018
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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