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C3MZY6

- RNP4_SULIA

UniProt

C3MZY6 - RNP4_SULIA

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Protein

Ribonuclease P protein component 4

Gene
rnp4, M1627_0042
Organism
Sulfolobus islandicus (strain M.16.27)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

Cofactori

Binds 1 zinc ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi57 – 571Zinc By similarity
Metal bindingi60 – 601Zinc By similarity
Metal bindingi83 – 831Zinc By similarity
Metal bindingi86 – 861Zinc By similarity

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-HAMAP
  2. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. tRNA 5'-leader removal Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciSISL427318:GH3D-42-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein component 4 (EC:3.1.26.5)
Short name:
RNase P component 4
Alternative name(s):
Rpp21
Gene namesi
Name:rnp4
Ordered Locus Names:M1627_0042
OrganismiSulfolobus islandicus (strain M.16.27)
Taxonomic identifieri427318 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
ProteomesiUP000002307: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. ribonuclease P complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 104104Ribonuclease P protein component 4UniRule annotationPRO_1000212862Add
BLAST

Interactioni

Subunit structurei

Consists of a catalytic RNA component and at least 4-5 protein subunits Reviewed prediction.

Protein-protein interaction databases

STRINGi427318.M1627_0042.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2023.
HOGENOMiHOG000230709.
KOiK03540.
OMAiRRGYCRR.

Family and domain databases

HAMAPiMF_00757. RNase_P_4.
InterProiIPR016432. RNase_P_comp-4.
IPR007175. Rpr2.
[Graphical view]
PANTHERiPTHR14742. PTHR14742. 1 hit.
PfamiPF04032. Rpr2. 1 hit.
[Graphical view]
PIRSFiPIRSF004878. RNase_P_4. 1 hit.

Sequencei

Sequence statusi: Complete.

C3MZY6-1 [UniParc]FASTAAdd to Basket

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MRIKNKIKKR IIELIDLAYI TARKGDLELA REYIKLAEMY SRKGRVKIPL    50
KYKRMFCRKC YTPLITGVTE RRRIRSKILI RTCLICNWQR RYVLSRNKGS 100
NKEN 104
Length:104
Mass (Da):12,594
Last modified:June 16, 2009 - v1
Checksum:i8BAF12946B56FF08
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001401 Genomic DNA. Translation: ACP54071.1.
RefSeqiYP_002842116.1. NC_012632.1.

Genome annotation databases

EnsemblBacteriaiACP54071; ACP54071; M1627_0042.
GeneIDi7812102.
KEGGisim:M1627_0042.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001401 Genomic DNA. Translation: ACP54071.1 .
RefSeqi YP_002842116.1. NC_012632.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 427318.M1627_0042.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACP54071 ; ACP54071 ; M1627_0042 .
GeneIDi 7812102.
KEGGi sim:M1627_0042.

Phylogenomic databases

eggNOGi COG2023.
HOGENOMi HOG000230709.
KOi K03540.
OMAi RRGYCRR.

Enzyme and pathway databases

BioCyci SISL427318:GH3D-42-MONOMER.

Family and domain databases

HAMAPi MF_00757. RNase_P_4.
InterProi IPR016432. RNase_P_comp-4.
IPR007175. Rpr2.
[Graphical view ]
PANTHERi PTHR14742. PTHR14742. 1 hit.
Pfami PF04032. Rpr2. 1 hit.
[Graphical view ]
PIRSFi PIRSF004878. RNase_P_4. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: M.16.27.

Entry informationi

Entry nameiRNP4_SULIA
AccessioniPrimary (citable) accession number: C3MZY6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: June 16, 2009
Last modified: July 9, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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