C3MZU9 (PHS_SULIA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative pterin-4-alpha-carbinolamine dehydratase
Short name=PHS
EC=4.2.1.96

Alternative name(s):
4-alpha-hydroxy-tetrahydropterin dehydratase
Pterin carbinolamine dehydratase
Short name=PCD

Gene names

Ordered Locus Names:

M1627_0005

Organism

Sulfolobus islandicus (strain M.16.27) [Complete proteome] [HAMAP]

Taxonomic identifier

427318 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus

Protein attributes

Sequence length	99 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O. HAMAP MF_00434
Sequence similarities	Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tetrahydrobiopterin biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	4-alpha-hydroxytetrahydrobiopterin dehydratase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 99	99	Putative pterin-4-alpha-carbinolamine dehydratase HAMAP MF_00434		PRO_1000206071

Sequences

	Sequence		Length	Mass (Da)
	C3MZU9 [UniParc]. Last modified June 16, 2009. Version 1. Checksum: 99230C895A1FD484	FASTA	99	11,408
	10 20 30 40 50 60 MSGISSKGLE ELKNNGWLIL EDGKKIKKEF KFKDFKQSID FLKDIQPSAD ALDHHPDVCI 70 80 90 YYNRVIVELT THDMGGLTDL DYKLAIKIDE LYKMKTSNL

References

[1]	"Biogeography of the Sulfolobus islandicus pan-genome." Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J. Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009) [PubMed: 19435847] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: M.16.27.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001401 Genomic DNA. Translation: ACP54034.1.
RefSeq	YP_002842079.1. NC_012632.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	C3MZU9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7812065.
GenomeReviews	Gene locus M1627_0005 in contig CP001401_GR.
KEGG	sim:M1627_0005.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	TVEIYTH.
ProtClustDB	CLSK2484518.
Family and domain databases
HAMAP	MF_00434. Pterin_4_alpha. [Tree]
InterPro	IPR001533. Trans/pterin_deHydtase. [Graphical view]
Gene3D	G3DSA:3.30.1360.20. Trans_pterinDh. 1 hit.
KO	K01724.
PANTHER	PTHR12599. Trans_pterinDh. 1 hit.
Pfam	PF01329. Pterin_4a. 1 hit. [Graphical view]
SUPFAM	SSF55248. Trans_pterinDh. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PHS_SULIA

Accession

Primary (citable) accession number: C3MZU9

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	June 16, 2009
Last modified:	November 16, 2011
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program