ID   IF2B_SULIM              Reviewed;         139 AA.
AC   C3MU32;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 1.
DT   27-MAR-2024, entry version 62.
DE   RecName: Full=Translation initiation factor 2 subunit beta {ECO:0000255|HAMAP-Rule:MF_00232};
DE   AltName: Full=aIF2-beta {ECO:0000255|HAMAP-Rule:MF_00232};
DE   AltName: Full=eIF-2-beta {ECO:0000255|HAMAP-Rule:MF_00232};
GN   Name=eif2b {ECO:0000255|HAMAP-Rule:MF_00232};
GN   OrderedLocusNames=M1425_0175;
OS   Sulfolobus islandicus (strain M.14.25 / Kamchatka #1).
OC   Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=427317;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M.14.25 / Kamchatka #1;
RX   PubMed=19435847; DOI=10.1073/pnas.0808945106;
RA   Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.;
RT   "Biogeography of the Sulfolobus islandicus pan-genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009).
CC   -!- FUNCTION: eIF-2 functions in the early steps of protein synthesis by
CC       forming a ternary complex with GTP and initiator tRNA.
CC       {ECO:0000255|HAMAP-Rule:MF_00232}.
CC   -!- SUBUNIT: Heterotrimer composed of an alpha, a beta and a gamma chain.
CC       {ECO:0000255|HAMAP-Rule:MF_00232}.
CC   -!- SIMILARITY: Belongs to the eIF-2-beta/eIF-5 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00232}.
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DR   EMBL; CP001400; ACP37066.1; -; Genomic_DNA.
DR   AlphaFoldDB; C3MU32; -.
DR   SMR; C3MU32; -.
DR   KEGG; sia:M1425_0175; -.
DR   HOGENOM; CLU_026663_3_1_2; -.
DR   Proteomes; UP000001350; Chromosome.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.30.170; -; 1.
DR   HAMAP; MF_00232; eIF_2_beta; 1.
DR   InterPro; IPR045196; IF2/IF5.
DR   InterPro; IPR004458; TIF2_bsu_arc.
DR   InterPro; IPR002735; Transl_init_fac_IF2/IF5_dom.
DR   InterPro; IPR016189; Transl_init_fac_IF2/IF5_N.
DR   InterPro; IPR016190; Transl_init_fac_IF2/IF5_Zn-bd.
DR   PANTHER; PTHR23001; EUKARYOTIC TRANSLATION INITIATION FACTOR; 1.
DR   PANTHER; PTHR23001:SF3; EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 2; 1.
DR   Pfam; PF01873; eIF-5_eIF-2B; 1.
DR   SMART; SM00653; eIF2B_5; 1.
DR   SUPFAM; SSF100966; Translation initiation factor 2 beta, aIF2beta, N-terminal domain; 1.
DR   SUPFAM; SSF75689; Zinc-binding domain of translation initiation factor 2 beta; 1.
PE   3: Inferred from homology;
KW   Initiation factor; Protein biosynthesis.
FT   CHAIN           1..139
FT                   /note="Translation initiation factor 2 subunit beta"
FT                   /id="PRO_1000204380"
SQ   SEQUENCE   139 AA;  15938 MW;  9A146D6E09F90867 CRC64;
     MSSEKEYVEM LDRLYSKLPE KGRKEGTQAL PNLIIFNIGN TTMIRNFAEY CDRIRREDKI
     CMKYLLKELA APGNVDDKGE LIIQGKFSSQ VINTLMERFL KAYVECSTCK SLDTVLKKEK
     KSWYIVCLAC GAQTPVKPL
//