C3MU32 (IF2B_SULIM) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Translation initiation factor 2 subunit beta

Alternative name(s):
aIF2-beta
eIF-2-beta

Gene names

Name:	eif2b
Ordered Locus Names:	M1425_0175

Organism

Sulfolobus islandicus (strain M.14.25 / Kamchatka #1) [Complete proteome] [HAMAP]

Taxonomic identifier

427317 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus › Sulfolobus islandicus

Protein attributes

Sequence length	139 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA By similarity. HAMAP-Rule MF_00232
Subunit structure	Heterotrimer composed of an alpha, a beta and a gamma chain By similarity.
Sequence similarities	Belongs to the eIF-2-beta/eIF-5 family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Molecular function	Initiation factor
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	translation initiation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 139	139	Translation initiation factor 2 subunit beta HAMAP-Rule MF_00232		PRO_1000204380

Sequences

	Sequence		Length	Mass (Da)
	C3MU32 [UniParc]. Last modified June 16, 2009. Version 1. Checksum: 9A146D6E09F90867	FASTA	139	15,938
	10 20 30 40 50 60 MSSEKEYVEM LDRLYSKLPE KGRKEGTQAL PNLIIFNIGN TTMIRNFAEY CDRIRREDKI 70 80 90 100 110 120 CMKYLLKELA APGNVDDKGE LIIQGKFSSQ VINTLMERFL KAYVECSTCK SLDTVLKKEK 130 KSWYIVCLAC GAQTPVKPL

References

[1]	"Biogeography of the Sulfolobus islandicus pan-genome." Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J. Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: M.14.25 / Kamchatka #1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001400 Genomic DNA. Translation: ACP37066.1.
RefSeq	YP_002828364.1. NC_012588.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	427317.M1425_0175.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACP37066; ACP37066; M1425_0175.
GeneID	7795592.
KEGG	sia:M1425_0175.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1601.
HOGENOM	HOG000107197.
KO	K03238.
OMA	EYVICRE.
ProtClustDB	PRK03988.
Enzyme and pathway databases
BioCyc	SISL427317:GI7C-179-MONOMER.
Family and domain databases
Gene3D	3.30.30.50. 1 hit.
HAMAP	MF_00232. eIF-2-beta.
InterPro	IPR004458. TIF2_bsu_arc. IPR002735. Transl_init_fac_IF2/IF5. IPR016189. Transl_init_fac_IF2/IF5_N. IPR016190. Transl_init_fac_IF2/IF5_Zn-bd. [Graphical view]
Pfam	PF01873. eIF-5_eIF-2B. 1 hit. [Graphical view]
SMART	SM00653. eIF2B_5. 1 hit. [Graphical view]
SUPFAM	SSF100966. Transl_init_fac_IF2/IF5_N. 1 hit. SSF75689. Transl_init_fac_IF2/IF5_Zn-bd. 1 hit.
ProtoNet	Search...

Entry information

Entry name

IF2B_SULIM

Accession

Primary (citable) accession number: C3MU32

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	June 16, 2009
Last modified:	May 1, 2013
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program