C3MR78 (IF6_SULIL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Translation initiation factor 6
Short name=aIF-6

Gene names

Name:	eif6
Ordered Locus Names:	LS215_1895

Organism

Sulfolobus islandicus (strain L.S.2.15 / Lassen #1) [Complete proteome] [HAMAP]

Taxonomic identifier

429572 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus › Sulfolobus islandicus

Protein attributes

Sequence length	223 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex By similarity. HAMAP-Rule MF_00032
Sequence similarities	Belongs to the eIF-6 family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Molecular function	Initiation factor
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	mature ribosome assembly Inferred from electronic annotation. Source: InterPro
Molecular_function	ribosome binding Inferred from electronic annotation. Source: InterPro translation initiation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 223	223	Translation initiation factor 6 HAMAP-Rule MF_00032		PRO_1000202009

Sequences

	Sequence		Length	Mass (Da)
	C3MR78 [UniParc]. Last modified June 16, 2009. Version 1. Checksum: EFA799EBF0764E0A	FASTA	223	24,503
	10 20 30 40 50 60 MNLQRLSIFG TDNIGVYIYT NNKYTVVPRG LDSETKENIV QILGTELIEA EISRSFLLGI 70 80 90 100 110 120 FISGNDNGIL LPKSTIDDEF RFLKENLRDC RVEVLNSKVT ALGNTILTNN KAALIYPEFN 130 140 150 160 170 180 DIEEKIIKET LGVEEIRRGK IAQMITVGSV GVVTNKGGLV HVDTSEKELK ELEKLFSVKI 190 200 210 220 DIGTVNFGSV FIRSGLVAND KGTLVGASTT GPEILRIQKA LGE

References

[1]	"Biogeography of the Sulfolobus islandicus pan-genome." Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J. Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: L.S.2.15 / Lassen #1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001399 Genomic DNA. Translation: ACP35891.1.
RefSeq	YP_002832536.1. NC_012589.1.
3D structure databases
ProteinModelPortal	C3MR78.
ModBase	Search...
Protein-protein interaction databases
STRING	429572.LS215_1895.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACP35891; ACP35891; LS215_1895.
GeneID	7799538.
KEGG	sis:LS215_1895.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1976.
HOGENOM	HOG000230604.
KO	K03264.
OMA	QFENSNE.
ProtClustDB	PRK04046.
Enzyme and pathway databases
BioCyc	SISL429572:GHOW-1963-MONOMER.
Family and domain databases
HAMAP	MF_00032. eIF-6.
InterPro	IPR002769. eIF6. [Graphical view]
PANTHER	PTHR10784. PTHR10784. 1 hit.
Pfam	PF01912. eIF-6. 1 hit. [Graphical view]
PIRSF	PIRSF006413. IF-6. 1 hit.
SMART	SM00654. eIF6. 1 hit. [Graphical view]
TIGRFAMs	TIGR00323. eIF-6. 1 hit.
ProtoNet	Search...

Entry information

Entry name

IF6_SULIL

Accession

Primary (citable) accession number: C3MR78

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	June 16, 2009
Last modified:	May 1, 2013
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program