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Protein

Putative adenylate kinase

Gene

LS215_1772

Organism
Sulfolobus islandicus (strain L.S.2.15 / Lassen #1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.UniRule annotation

Catalytic activityi

ATP + AMP = 2 ADP.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei100 – 1001ATPUniRule annotation
Binding sitei104 – 1041ATPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi10 – 156ATPUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSISL429572:GHOW-1835-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative adenylate kinaseUniRule annotation (EC:2.7.4.3UniRule annotation)
Short name:
AKUniRule annotation
Alternative name(s):
ATP-AMP transphosphorylaseUniRule annotation
Gene namesi
Ordered Locus Names:LS215_1772
OrganismiSulfolobus islandicus (strain L.S.2.15 / Lassen #1)
Taxonomic identifieri429572 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
Proteomesi
  • UP000001747 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 187187Putative adenylate kinasePRO_1000202084Add
BLAST

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni30 – 5324NMPbindUniRule annotationAdd
BLAST
Regioni103 – 11311LIDUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the adenylate kinase family. AK6 subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000224471.
KOiK18532.
OMAiIVLRCHP.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00039. Adenylate_kinase_AK6.
InterProiIPR020618. Adenyl_kinase_AK6.
IPR027417. P-loop_NTPase.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

C3MQV5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIIIVTGTPG VGKTIASKKL SEALNLNYLS LSQFVIENKL YTEYDELRQS
60 70 80 90 100
YIIDEDKVKE ELEKIISTSH LVIETIYPSL VSTADLVVVL RKNPFSLYNE
110 120 130 140 150
LKGRGWADIK VAENVEAEIL GVISQEAREA FKDKVCEVDT TEMSTEQILN
160 170 180
KILNKQCDGP IEWLVDTKVQ RFLEELDKII SSYENDI
Length:187
Mass (Da):21,261
Last modified:June 16, 2009 - v1
Checksum:iCC649677CBDF5938
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001399 Genomic DNA. Translation: ACP35768.1.
RefSeqiWP_012713886.1. NC_012589.1.

Genome annotation databases

EnsemblBacteriaiACP35768; ACP35768; LS215_1772.
GeneIDi7799409.
KEGGisis:LS215_1772.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001399 Genomic DNA. Translation: ACP35768.1.
RefSeqiWP_012713886.1. NC_012589.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACP35768; ACP35768; LS215_1772.
GeneIDi7799409.
KEGGisis:LS215_1772.

Phylogenomic databases

HOGENOMiHOG000224471.
KOiK18532.
OMAiIVLRCHP.

Enzyme and pathway databases

BioCyciSISL429572:GHOW-1835-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00039. Adenylate_kinase_AK6.
InterProiIPR020618. Adenyl_kinase_AK6.
IPR027417. P-loop_NTPase.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: L.S.2.15 / Lassen #1.

Entry informationi

Entry nameiKAD6_SULIL
AccessioniPrimary (citable) accession number: C3MQV5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: June 16, 2009
Last modified: November 11, 2015
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.