C3MPV8 (C3MPV8_SULIL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Indole-3-glycerol phosphate synthase HAMAP MF_00134
Short name=IGPS HAMAP MF_00134
EC=4.1.1.48 HAMAP MF_00134

Gene names

Name:	trpC HAMAP MF_00134
Ordered Locus Names:	LS215_1413

Organism

Sulfolobus islandicus (strain L.S.2.15 / Lassen #1) [Complete proteome] [HAMAP] EMBL ACP35421.1

Taxonomic identifier

429572 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus

Protein attributes

Sequence length	248 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134
Sequence similarities	Belongs to the TrpC family. HAMAP MF_00134

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis HAMAP MF_00134
Molecular function	Decarboxylase HAMAP MF_00134 Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	indole-3-glycerol-phosphate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C3MPV8 [UniParc]. Last modified June 16, 2009. Version 1. Checksum: F4A47FE398FD333C	FASTA	248	28,535
	10 20 30 40 50 60 MPRYLKGWLK DVVQLSLRRP SFRTSRQRPI ISLNKRILEF NVRNVTAIIA EYKRKSPSGL 70 80 90 100 110 120 DVERDPIEYA KFMEKYAVGL SVLTEEKYFN GSYEILRKIA SSVSIPILMK DFIVKESQID 130 140 150 160 170 180 DAYNLGADTV LLIVKILTER ELESLMEYTR SYGMEPLVEI NDEKDLEIAL RIGAKFIGVN 190 200 210 220 230 240 SRDLETLEIN KENQRKLLSM IPSDVIKVAE SGISERNEIE ELRKLGVNAF LIGSSLMQNP EKIKEFIL

References

[1]

"Biogeography of the Sulfolobus islandicus pan-genome." Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J. Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009) [PubMed: 19435847] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: L.S.2.15 EMBL ACP35421.1.

[2]

US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sims D.R., Brettin T., Bruce D., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Anderson I., Whitaker R.J., Richardson P. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: L.S.2.15 EMBL ACP35421.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001399 Genomic DNA. Translation: ACP35421.1.
RefSeq	YP_002832066.1. NC_012589.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	C3MPV8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7797931.
GenomeReviews	Gene locus LS215_1413 in contig CP001399_GR.
KEGG	sis:LS215_1413.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	FETDINT.
ProtClustDB	PRK00278.
Family and domain databases
HAMAP	MF_00134_A. IGPS_A. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR013798. Indole-3-glycerol_P_synth. IPR001468. Indole-3-GlycerolPSynthase_CS. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01609.
Pfam	PF00218. IGPS. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
PROSITE	PS00614. IGPS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C3MPV8_SULIL

Accession

Primary (citable) accession number: C3MPV8

Entry history

Integrated into UniProtKB/TrEMBL:	June 16, 2009
Last sequence update:	June 16, 2009
Last modified:	January 25, 2012
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)