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C3MPE9 (C3MPE9_SULIL) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
N5-carboxyaminoimidazole ribonucleotide mutase PIRNR PIRNR001338

Short name=N5-CAIR mutase PIRNR PIRNR001338
EC=5.4.99.18 PIRNR PIRNR001338
Gene names
Ordered Locus Names:LS215_1251
OrganismSulfolobus islandicus (strain L.S.2.15 / Lassen #1) [Complete proteome] [HAMAP] EMBL ACP35262.1
Taxonomic identifier429572 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus

Protein attributes

Sequence length158 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) By similarity. PIRNR PIRNR001338

Catalytic activity

5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate. PIRNR PIRNR001338

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2. PIRNR PIRNR001338

Sequence similarities

Belongs to the AIR carboxylase family. PIRNR PIRNR001338

Sequences

Sequence LengthMass (Da)Tools
C3MPE9 [UniParc].

Last modified June 16, 2009. Version 1.
Checksum: 5811EEAA8509A8A4

FASTA15817,010
        10         20         30         40         50         60 
MPKVAVIMGS RNDWEYMKEA VEILKQFGVD YEARVVSAHR TPEFMMQYAK EAEKRGIEVI 

        70         80         90        100        110        120 
IAGAGGAAHL PGMVASLTSL PVIGVPIPSK NLNGLDSLLS IVQMPYGVPV ATVAIGGAKN 

       130        140        150 
AALLAIRILG IKYKDLAEKI KKFSEDMRND VLNTGLEA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001399 Genomic DNA. Translation: ACP35262.1.
RefSeqYP_002831907.1. NC_012589.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGC3MPE9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7797760.
GenomeReviewsGene locus LS215_1251 in contig CP001399_GR.
KEGGsis:LS215_1251.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMALIMGSDS.
ProtClustDBCLSK802986.

Family and domain databases

InterProIPR024694. N5-CAIR_mutase_PurE.
IPR000031. N5-CAIR_Mutase_PurE_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.7700. AIR_carboxyl. 1 hit.
KOK01588.
PfamPF00731. AIRC. 1 hit.
[Graphical view]
PIRSFPIRSF001338. AIR_carboxylase. 1 hit.
SMARTSM01001. AIRC. 1 hit.
[Graphical view]
SUPFAMSSF52255. AIR_carboxyl. 1 hit.
TIGRFAMsTIGR01162. PurE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC3MPE9_SULIL
AccessionPrimary (citable) accession number: C3MPE9
Entry history
Integrated into UniProtKB/TrEMBL: June 16, 2009
Last sequence update: June 16, 2009
Last modified: January 25, 2012
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)