C3MJB8 (RNP4_SULIL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component 4
Short name=RNase P component 4
EC=3.1.26.5

Gene names

Name:	rnp4
Ordered Locus Names:	LS215_0042

Organism

Sulfolobus islandicus (strain L.S.2.15 / Lassen #1) [Complete proteome] [HAMAP]

Taxonomic identifier

429572 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus › Sulfolobus islandicus

Protein attributes

Sequence length	104 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP-Rule MF_00757
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00757
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 4 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Molecular_function	ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 104	104	Ribonuclease P protein component 4 HAMAP-Rule MF_00757		PRO_1000212864

Sequences

	Sequence		Length	Mass (Da)
	C3MJB8 [UniParc]. Last modified June 16, 2009. Version 1. Checksum: 8ABE0C9B7A48F108	FASTA	104	12,622
	10 20 30 40 50 60 MRIKNKIKKR IIELIELAYI TARKGDLELA REYIKLAEMY SRKGRIKIPL KYKRMFCRKC 70 80 90 100 YTPLITGVTE RRRIRSKILI RTCLICNWQR RYVLSRNKGS NKEN

References

[1]	"Biogeography of the Sulfolobus islandicus pan-genome." Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J. Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: L.S.2.15 / Lassen #1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001399 Genomic DNA. Translation: ACP34196.1.
RefSeq	YP_002830841.1. NC_012589.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	429572.LS215_0042.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACP34196; ACP34196; LS215_0042.
GeneID	7797107.
KEGG	sis:LS215_0042.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2023.
HOGENOM	HOG000230709.
KO	K03540.
OMA	PPRYIRR.
ProtClustDB	CLSK803260.
Enzyme and pathway databases
BioCyc	SISL429572:GHOW-42-MONOMER.
Family and domain databases
HAMAP	MF_00757. RNase_P_4.
InterPro	IPR016432. RNase_P_comp-4. IPR007175. Rpr2. [Graphical view]
Pfam	PF04032. Rpr2. 1 hit. [Graphical view]
PIRSF	PIRSF004878. RNase_P_4. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RNP4_SULIL

Accession

Primary (citable) accession number: C3MJB8

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	June 16, 2009
Last modified:	May 1, 2013
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program