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C3MJB8 (RNP4_SULIL) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease P protein component 4

Short name=RNase P component 4
EC=3.1.26.5
Alternative name(s):
Rpp21
Gene names
Name:rnp4
Ordered Locus Names:LS215_0042
OrganismSulfolobus islandicus (strain L.S.2.15 / Lassen #1) [Complete proteome] [HAMAP]
Taxonomic identifier429572 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus

Protein attributes

Sequence length104 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP-Rule MF_00757

Catalytic activity

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00757

Cofactor

Binds 1 zinc ion per subunit By similarity. HAMAP-Rule MF_00757

Subunit structure

Consists of a catalytic RNA component and at least 4-5 protein subunits Potential.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00757.

Sequence similarities

Belongs to the eukaryotic/archaeal RNase P protein component 4 family.

Ontologies

Keywords
   Biological processtRNA processing
   Cellular componentCytoplasm
   LigandMetal-binding
Zinc
   Molecular functionEndonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtRNA 5'-leader removal

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

ribonuclease P complex

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionribonuclease P activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

zinc ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 104104Ribonuclease P protein component 4 HAMAP-Rule MF_00757
PRO_1000212864

Sites

Metal binding571Zinc By similarity
Metal binding601Zinc By similarity
Metal binding831Zinc By similarity
Metal binding861Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
C3MJB8 [UniParc].

Last modified June 16, 2009. Version 1.
Checksum: 8ABE0C9B7A48F108

FASTA10412,622
        10         20         30         40         50         60 
MRIKNKIKKR IIELIELAYI TARKGDLELA REYIKLAEMY SRKGRIKIPL KYKRMFCRKC 

        70         80         90        100 
YTPLITGVTE RRRIRSKILI RTCLICNWQR RYVLSRNKGS NKEN 

« Hide

References

[1]"Biogeography of the Sulfolobus islandicus pan-genome."
Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.
Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: L.S.2.15 / Lassen #1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001399 Genomic DNA. Translation: ACP34196.1.
RefSeqYP_002830841.1. NC_012589.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING429572.LS215_0042.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACP34196; ACP34196; LS215_0042.
GeneID7797107.
KEGGsis:LS215_0042.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2023.
HOGENOMHOG000230709.
KOK03540.
OMARRGYCRR.

Enzyme and pathway databases

BioCycSISL429572:GHOW-42-MONOMER.

Family and domain databases

HAMAPMF_00757. RNase_P_4.
InterProIPR016432. RNase_P_comp-4.
IPR007175. Rpr2.
[Graphical view]
PANTHERPTHR14742. PTHR14742. 1 hit.
PfamPF04032. Rpr2. 1 hit.
[Graphical view]
PIRSFPIRSF004878. RNase_P_4. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRNP4_SULIL
AccessionPrimary (citable) accession number: C3MJB8
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: June 16, 2009
Last modified: July 9, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families