C3MJ30 (PTH_SULIL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Peptidyl-tRNA hydrolase
Short name=PTH
EC=3.1.1.29

Gene names

Name:	pth
Ordered Locus Names:	LS215_2125

Organism

Sulfolobus islandicus (strain L.S.2.15 / Lassen #1) [Complete proteome] [HAMAP]

Taxonomic identifier

429572 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus

Protein attributes

Sequence length	120 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis By similarity. HAMAP MF_00628
Catalytic activity	N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. HAMAP MF_00628
Subcellular location	Cytoplasm By similarity HAMAP MF_00628.
Sequence similarities	Belongs to the PTH2 family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	aminoacyl-tRNA hydrolase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 120	120	Peptidyl-tRNA hydrolase HAMAP MF_00628		PRO_1000212316

Sequences

	Sequence		Length	Mass (Da)
	C3MJ30 [UniParc]. Last modified June 16, 2009. Version 1. Checksum: 076EDE7E014F58A3	FASTA	120	13,147
	10 20 30 40 50 60 MVKMVIVVRS DIKMGKGKMA AQVAHAAVTL VISIINSNNS RWKEWLNEWL QQGQPKIVVK 70 80 90 100 110 120 ANSLDEIILR SKKAETMNLP FSIIEDAGKT QLEPGTITCL GIGPAPENLI DPITGDLKLL

References

[1]	"Biogeography of the Sulfolobus islandicus pan-genome." Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J. Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009) [PubMed: 19435847] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: L.S.2.15 / Lassen #1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001399 Genomic DNA. Translation: ACP36117.1.
RefSeq	YP_002832762.1. NC_012589.1.
3D structure databases
ProteinModelPortal	C3MJ30.
ModBase	Search...
Protein-protein interaction databases
STRING	C3MJ30.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7798100.
GenomeReviews	Gene locus LS215_2125 in contig CP001399_GR.
KEGG	sis:LS215_2125.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	KSLVMEY.
ProtClustDB	PRK04322.
Family and domain databases
HAMAP	MF_00628. Pept_tRNA_hydro_arch. [Tree]
InterPro	IPR023476. Pep_tRNA_hydro_II_dom. IPR002833. Pep_tRNA_hydro_PTH2. [Graphical view]
Gene3D	G3DSA:3.40.1490.10. G3DSA:3.40.1490.10. 1 hit.
KO	K04794.
Pfam	PF01981. PTH2. 1 hit. [Graphical view]
SUPFAM	SSF102462. SSF102462. 1 hit.
TIGRFAMs	TIGR00283. Arch_pth2. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PTH_SULIL

Accession

Primary (citable) accession number: C3MJ30

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	June 16, 2009
Last modified:	November 16, 2011
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program