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C3MJ22 (GSA_SULIL) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamate-1-semialdehyde 2,1-aminomutase

Short name=GSA
EC=5.4.3.8
Alternative name(s):
Glutamate-1-semialdehyde aminotransferase
Short name=GSA-AT
Gene names
Name:hemL
Ordered Locus Names:LS215_2116
OrganismSulfolobus islandicus (strain L.S.2.15 / Lassen #1) [Complete proteome] [HAMAP]
Taxonomic identifier429572 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus

Protein attributes

Sequence length426 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processPorphyrin biosynthesis
   Cellular componentCytoplasm
   LigandPyridoxal phosphate
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processprotoporphyrinogen IX biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglutamate-1-semialdehyde 2,1-aminomutase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

pyridoxal phosphate binding

Inferred from electronic annotation. Source: InterPro

transaminase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 426426Glutamate-1-semialdehyde 2,1-aminomutase HAMAP-Rule MF_00375
PRO_0000382413

Amino acid modifications

Modified residue2681N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
C3MJ22 [UniParc].

Last modified June 16, 2009. Version 1.
Checksum: 82BFEC7AB6396FA3

FASTA42647,261
        10         20         30         40         50         60 
MDKGRCTILN SEELWAQARQ LFAGGVNSPV RAAVKPFPFY VERGKGAYIY TVEGNKFIDY 

        70         80         90        100        110        120 
VLGYGPLILG HSPESVKRKI IEQLEKGWLF GTPSKLEIEL AKKISSHIPS AQKIRFVNSG 

       130        140        150        160        170        180 
TEATMAAIRL ARGYSKRSKI LKFSGNYHGA HDYTLVEAGS AATEYNVTTS DGIPMEIMKT 

       190        200        210        220        230        240 
VEICEFNDLD CVDKKLRNED IAAALLEPIM GNAGVILPEK GFLSGLRELT KSYNSLLIFD 

       250        260        270        280        290        300 
EVITGFRIDI GGAQSYYQIY PDITTLGKII GGGFPIGAVA GKAEIIDNFT PAGRVFNAGT 

       310        320        330        340        350        360 
FNANPISMIA GIATIEELEK EYPYNIANKA SKTLVEELER LLKIKHTINH IGSMFQVFFG 

       370        380        390        400        410        420 
IDKVRNYSDA KRANKEYYIK FHERLLKERV FIPPSQYETI FTSAAHEDDV VNDTIDKLAK 


VIGELS 

« Hide

References

[1]"Biogeography of the Sulfolobus islandicus pan-genome."
Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.
Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: L.S.2.15 / Lassen #1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001399 Genomic DNA. Translation: ACP36109.1.
RefSeqYP_002832754.1. NC_012589.1.

3D structure databases

ProteinModelPortalC3MJ22.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING429572.LS215_2116.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACP36109; ACP36109; LS215_2116.
GeneID7798091.
KEGGsis:LS215_2116.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0001.
HOGENOMHOG000020210.
KOK01845.
OMAHGHANAF.

Enzyme and pathway databases

BioCycSISL429572:GHOW-2199-MONOMER.
UniPathwayUPA00251; UER00317.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
HAMAPMF_00375. HemL_aminotrans_3.
InterProIPR004639. 4pyrrol_synth_GluAld_NH2Trfase.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERPTHR11986. PTHR11986. 1 hit.
PfamPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMSSF53383. SSF53383. 1 hit.
TIGRFAMsTIGR00713. hemL. 1 hit.
PROSITEPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGSA_SULIL
AccessionPrimary (citable) accession number: C3MJ22
Entry history
Integrated into UniProtKB/Swiss-Prot: September 1, 2009
Last sequence update: June 16, 2009
Last modified: May 14, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways