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Protein

Inositol 2-dehydrogenase

Gene

iolG

Organism
Rhizobium sp. (strain NGR234)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).UniRule annotation

Catalytic activityi

Myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciSFRE394:GBYN-2594-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Inositol 2-dehydrogenaseUniRule annotation (EC:1.1.1.18UniRule annotation)
Alternative name(s):
Myo-inositol 2-dehydrogenaseUniRule annotation
Short name:
MI 2-dehydrogenaseUniRule annotation
Gene namesi
Name:iolGUniRule annotation
Ordered Locus Names:NGR_c26010
OrganismiRhizobium sp. (strain NGR234)
Taxonomic identifieri394 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
Proteomesi
  • UP000001054 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 340340Inositol 2-dehydrogenasePRO_1000187319Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi394.NGR_c26010.

Structurei

3D structure databases

ProteinModelPortaliC3MH72.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Gfo/Idh/MocA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DRI. Bacteria.
COG0673. LUCA.
HOGENOMiHOG000227439.
KOiK00010.
OMAiRRFDKGY.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_01671. IolG.
InterProiIPR023794. MI/DCI_dehydrogenase.
IPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
[Graphical view]
PfamiPF01408. GFO_IDH_MocA. 1 hit.
[Graphical view]
SUPFAMiSSF51735. SSF51735. 1 hit.

Sequencei

Sequence statusi: Complete.

C3MH72-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLRVGVIGT GMIGQDHIRR LTQVLSAVEV VAVSDIDGAR AAAVAPQGAD
60 70 80 90 100
VYAAAGDLIR SETVEAVVIC SWGPAHEEQL LDCIAAGKPV FCEKPLVTTA
110 120 130 140 150
AAALRVMEAE VAFGRRLVQV GFMRRFDADY RRLKATLDAG VLGAPLMFHS
160 170 180 190 200
THRNASVPEG LYTSDMPLND TLVHDAYISR WLLNDEVTGV EVRVPRRSRR
210 220 230 240 250
GGELRDPVVV LLHMGSGALV DVEISVNIAY GYDIRGEVSC EEGTASLPLR
260 270 280 290 300
PATVIRDIHG VRQPVPADWR ERFIEAYDQE FREWIVAAAQ GTATGPSTWD
310 320 330 340
GYAATLVADA ALRAAESGAL EPVRMCQRPS LYGPTLEAAR
Length:340
Mass (Da):36,744
Last modified:June 16, 2009 - v1
Checksum:iFD78825B92DDDE27
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001389 Genomic DNA. Translation: ACP26358.1.
RefSeqiWP_012709115.1. NC_012587.1.
YP_002827111.1. NC_012587.1.

Genome annotation databases

EnsemblBacteriaiACP26358; ACP26358; NGR_c26010.
GeneIDi7790257.
KEGGirhi:NGR_c26010.
PATRICi32311653. VBIRhiSp122450_5424.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001389 Genomic DNA. Translation: ACP26358.1.
RefSeqiWP_012709115.1. NC_012587.1.
YP_002827111.1. NC_012587.1.

3D structure databases

ProteinModelPortaliC3MH72.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi394.NGR_c26010.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACP26358; ACP26358; NGR_c26010.
GeneIDi7790257.
KEGGirhi:NGR_c26010.
PATRICi32311653. VBIRhiSp122450_5424.

Phylogenomic databases

eggNOGiENOG4105DRI. Bacteria.
COG0673. LUCA.
HOGENOMiHOG000227439.
KOiK00010.
OMAiRRFDKGY.

Enzyme and pathway databases

BioCyciSFRE394:GBYN-2594-MONOMER.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_01671. IolG.
InterProiIPR023794. MI/DCI_dehydrogenase.
IPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
[Graphical view]
PfamiPF01408. GFO_IDH_MocA. 1 hit.
[Graphical view]
SUPFAMiSSF51735. SSF51735. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NGR234.

Entry informationi

Entry nameiIOLG_RHISN
AccessioniPrimary (citable) accession number: C3MH72
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: June 16, 2009
Last modified: December 9, 2015
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.