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C3MFW1

- PNCB_RHISN

UniProt

C3MFW1 - PNCB_RHISN

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Protein
Nicotinate phosphoribosyltransferase
Gene
pncB, NGR_c02120
Organism
Rhizobium sp. (strain NGR234)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity.UniRule annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ligase activity Source: UniProtKB-KW
  2. nicotinate phosphoribosyltransferase activity Source: InterPro
  3. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. NAD biosynthetic process Source: UniProtKB-UniPathway
  2. nicotinate nucleotide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesis

Enzyme and pathway databases

BioCyciSFRE394:GBYN-211-MONOMER.
UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferase (EC:6.3.4.21)
Short name:
NAPRTase
Gene namesi
Name:pncB
Ordered Locus Names:NGR_c02120
OrganismiRhizobium sp. (strain NGR234)
Taxonomic identifieri394 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
ProteomesiUP000001054: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 434434Nicotinate phosphoribosyltransferaseUniRule annotation
PRO_1000191531Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi394.NGR_c02120.

Structurei

3D structure databases

ProteinModelPortaliC3MFW1.

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.

Phylogenomic databases

eggNOGiCOG1488.
HOGENOMiHOG000284929.
KOiK00763.
OMAiQAVFHRY.
OrthoDBiEOG6X10XB.

Family and domain databases

HAMAPiMF_00570. NAPRTase.
InterProiIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

C3MFW1-1 [UniParc]FASTAAdd to Basket

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MPKTDIARRV YNHTWKLDPI IRSLLDTDFY KLLMLQMIWQ LYPDVDATFS    50
LINRTKTVRL AEEIDEQELR DQLDHARTLR FSKKEMIWLA GNTFYGRKQI 100
FSPEFLSWLA RFRLPEYELS RRDGQFELTF RGRWVETTMW EIPALAIINE 150
LRSRAAMKGL GPFTLDVLYA RAKAKMWSKV EQLRQYPNLR ISDFGTRRRH 200
SFLWQRWCVE ALKEGIGASF SGSSNVLLAM DNDLEALGTN AHELPMVAAA 250
LARNDKELAA APYKVLQDWN QLYGGNLLIV LPDSFGTAAF LRNAPDWVAD 300
WTGFRPDSAP PVEGGEKILA WWKKKGRDPR DKLLIFSDGL DVDTIIKTYR 350
HFEGRVRMSF GWGTNLTNDF AGCAPTEIGG LNPISIVCKV SEANGRPAVK 400
LSDNPRKATG DPAEVERYLK FFGTEDFVEQ TVRV 434
Length:434
Mass (Da):49,809
Last modified:June 16, 2009 - v1
Checksum:i462B82671F27648C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001389 Genomic DNA. Translation: ACP24012.1.
RefSeqiWP_012706797.1. NC_012587.1.
YP_002824765.1. NC_012587.1.

Genome annotation databases

EnsemblBacteriaiACP24012; ACP24012; NGR_c02120.
GeneIDi7790790.
KEGGirhi:NGR_c02120.
PATRICi32306764. VBIRhiSp122450_3012.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001389 Genomic DNA. Translation: ACP24012.1 .
RefSeqi WP_012706797.1. NC_012587.1.
YP_002824765.1. NC_012587.1.

3D structure databases

ProteinModelPortali C3MFW1.
ModBasei Search...

Protein-protein interaction databases

STRINGi 394.NGR_c02120.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACP24012 ; ACP24012 ; NGR_c02120 .
GeneIDi 7790790.
KEGGi rhi:NGR_c02120.
PATRICi 32306764. VBIRhiSp122450_3012.

Phylogenomic databases

eggNOGi COG1488.
HOGENOMi HOG000284929.
KOi K00763.
OMAi QAVFHRY.
OrthoDBi EOG6X10XB.

Enzyme and pathway databases

UniPathwayi UPA00253 ; UER00457 .
BioCyci SFRE394:GBYN-211-MONOMER.

Family and domain databases

HAMAPi MF_00570. NAPRTase.
InterProi IPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view ]
PANTHERi PTHR11098. PTHR11098. 1 hit.
Pfami PF04095. NAPRTase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000484. NAPRT. 1 hit.
SUPFAMi SSF51690. SSF51690. 1 hit.
TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NGR234.

Entry informationi

Entry nameiPNCB_RHISN
AccessioniPrimary (citable) accession number: C3MFW1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: June 16, 2009
Last modified: September 3, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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