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C3MFW1 (PNCB_RHISN) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:NGR_c02120
OrganismRhizobium sp. (strain NGR234) [Complete proteome] [HAMAP]
Taxonomic identifier394 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium

Protein attributes

Sequence length434 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 434434Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_1000191531

Sequences

Sequence LengthMass (Da)Tools
C3MFW1 [UniParc].

Last modified June 16, 2009. Version 1.
Checksum: 462B82671F27648C

FASTA43449,809
        10         20         30         40         50         60 
MPKTDIARRV YNHTWKLDPI IRSLLDTDFY KLLMLQMIWQ LYPDVDATFS LINRTKTVRL 

        70         80         90        100        110        120 
AEEIDEQELR DQLDHARTLR FSKKEMIWLA GNTFYGRKQI FSPEFLSWLA RFRLPEYELS 

       130        140        150        160        170        180 
RRDGQFELTF RGRWVETTMW EIPALAIINE LRSRAAMKGL GPFTLDVLYA RAKAKMWSKV 

       190        200        210        220        230        240 
EQLRQYPNLR ISDFGTRRRH SFLWQRWCVE ALKEGIGASF SGSSNVLLAM DNDLEALGTN 

       250        260        270        280        290        300 
AHELPMVAAA LARNDKELAA APYKVLQDWN QLYGGNLLIV LPDSFGTAAF LRNAPDWVAD 

       310        320        330        340        350        360 
WTGFRPDSAP PVEGGEKILA WWKKKGRDPR DKLLIFSDGL DVDTIIKTYR HFEGRVRMSF 

       370        380        390        400        410        420 
GWGTNLTNDF AGCAPTEIGG LNPISIVCKV SEANGRPAVK LSDNPRKATG DPAEVERYLK 

       430 
FFGTEDFVEQ TVRV 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001389 Genomic DNA. Translation: ACP24012.1.
RefSeqYP_002824765.1. NC_012587.1.

3D structure databases

ProteinModelPortalC3MFW1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING394.NGR_c02120.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACP24012; ACP24012; NGR_c02120.
GeneID7790790.
KEGGrhi:NGR_c02120.
PATRIC32306764. VBIRhiSp122450_3012.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284929.
KOK00763.
OMAKLTMQCA.
OrthoDBEOG6X10XB.
ProtClustDBPRK05321.

Enzyme and pathway databases

BioCycSFRE394:GBYN-211-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERPTHR11098:SF1. PTHR11098:SF1. 1 hit.
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_RHISN
AccessionPrimary (citable) accession number: C3MFW1
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: June 16, 2009
Last modified: March 19, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways