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C3MF41 (ARGB_RHISN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Acetylglutamate kinase

EC=2.7.2.8
Alternative name(s):
N-acetyl-L-glutamate 5-phosphotransferase
NAG kinase
Short name=AGK
Gene names
Name:argB
Ordered Locus Names:NGR_c00740
OrganismRhizobium sp. (strain NGR234) [Complete proteome] [HAMAP]
Taxonomic identifier394 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium

Protein attributes

Sequence length295 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate. HAMAP-Rule MF_00082

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4. HAMAP-Rule MF_00082

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00082.

Sequence similarities

Belongs to the acetylglutamate kinase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Arginine biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginine biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

proline biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

acetylglutamate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glutamate 5-kinase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 295295Acetylglutamate kinase HAMAP-Rule MF_00082
PRO_1000118360

Regions

Region66 – 672Substrate binding By similarity

Sites

Binding site881Substrate By similarity
Binding site1931Substrate By similarity
Site311Transition state stabilizer By similarity
Site2531Transition state stabilizer By similarity

Sequences

Sequence LengthMass (Da)Tools
C3MF41 [UniParc].

Last modified June 16, 2009. Version 1.
Checksum: 9032A7D3B3320594

FASTA29531,221
        10         20         30         40         50         60 
MSASESEIQA RLLAQALPYM QRYENKTIVV KYGGHAMGNP ELGRAFASDI ALLKQSGVNP 

        70         80         90        100        110        120 
IVVHGGGPQI GAMLNKMGIE SKFEGGLRVT DEKTVEIVEM VLAGSINKEI VALINQTGEW 

       130        140        150        160        170        180 
AIGLCGKDGN MVFAEKARKT IKDPDSNIER ILDLGFVGEV VEVDRTLLDL LARSEMIPVI 

       190        200        210        220        230        240 
APVAPGRDGH TYNINADTFA GAIAGALNAT RLLFLTDVPG VLDKQGNLIK ELSVAQAHAL 

       250        260        270        280        290 
IADGTISGGM IPKVETCMEA IKAGVQGVVI LNGKTAHSVL LEIFTERGAG TLIVP 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001389 Genomic DNA. Translation: ACP23878.1.
RefSeqYP_002824631.1. NC_012587.1.

3D structure databases

ProteinModelPortalC3MF41.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING394.NGR_c00740.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACP23878; ACP23878; NGR_c00740.
GeneID7790653.
KEGGrhi:NGR_c00740.
PATRIC32306468. VBIRhiSp122450_2867.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0548.
HOGENOMHOG000233259.
KOK00930.
OMAEGIGTMV.
OrthoDBEOG6T1WVF.
ProtClustDBPRK00942.

Enzyme and pathway databases

BioCycSFRE394:GBYN-74-MONOMER.
UniPathwayUPA00068; UER00107.

Family and domain databases

Gene3D3.40.1160.10. 1 hit.
HAMAPMF_00082_B. ArgB_B.
InterProIPR004662. AcgluKinase.
IPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu/AcGlu_kinase.
[Graphical view]
PfamPF00696. AA_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000728. NAGK. 1 hit.
PRINTSPR00474. GLU5KINASE.
SUPFAMSSF53633. SSF53633. 1 hit.
TIGRFAMsTIGR00761. argB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameARGB_RHISN
AccessionPrimary (citable) accession number: C3MF41
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: June 16, 2009
Last modified: February 19, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways