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C3MD81

- GLSA_RHISN

UniProt

C3MD81 - GLSA_RHISN

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Protein
Glutaminase
Gene
glsA, NGR_c16350
Organism
Rhizobium sp. (strain NGR234)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei70 – 701Substrate By similarity
Binding sitei120 – 1201Substrate By similarity
Binding sitei166 – 1661Substrate By similarity
Binding sitei173 – 1731Substrate By similarity
Binding sitei197 – 1971Substrate By similarity
Binding sitei249 – 2491Substrate By similarity
Binding sitei267 – 2671Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciSFRE394:GBYN-1632-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:NGR_c16350
OrganismiRhizobium sp. (strain NGR234)
Taxonomic identifieri394 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
ProteomesiUP000001054: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 315315GlutaminaseUniRule annotation
PRO_1000132910Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi394.NGR_c16350.

Structurei

3D structure databases

ProteinModelPortaliC3MD81.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiQRARRIN.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

C3MD81-1 [UniParc]FASTAAdd to Basket

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MPEQKAPQDL QLILDDIYRE LTPRLGEGKV ADYIPQLARV NPQHFGMAIV    50
TTGGEVHRVG DAEVPFSIQS ISKVFTLTLA LGKHGENIWH RVGREPSGSA 100
FNSIVQLEHE GGKPRNPFIN AGAITISDLI LAGHTPKELI GEIVRFVRYL 150
ADDENIVIDH EVARSETVTG FRNFALASFM RSFGRLDHPV EHVLGVYFHH 200
CALAMTCSQL AKAGLFLAAG GTNPLTGHSV VSRQRARRIN ALMLTCGHYD 250
GSGDFAYRVG LPGKSGVGGG IMAVAPGKAS IAVWSPGLNE NGNSLLGSLA 300
LEMLAARTGW SVFGP 315
Length:315
Mass (Da):33,838
Last modified:June 16, 2009 - v1
Checksum:i7C0303E270407796
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001389 Genomic DNA. Translation: ACP25400.1.
RefSeqiWP_012708169.1. NC_012587.1.
YP_002826153.1. NC_012587.1.

Genome annotation databases

EnsemblBacteriaiACP25400; ACP25400; NGR_c16350.
GeneIDi7790915.
KEGGirhi:NGR_c16350.
PATRICi32309701. VBIRhiSp122450_4451.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001389 Genomic DNA. Translation: ACP25400.1 .
RefSeqi WP_012708169.1. NC_012587.1.
YP_002826153.1. NC_012587.1.

3D structure databases

ProteinModelPortali C3MD81.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 394.NGR_c16350.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACP25400 ; ACP25400 ; NGR_c16350 .
GeneIDi 7790915.
KEGGi rhi:NGR_c16350.
PATRICi 32309701. VBIRhiSp122450_4451.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi QRARRIN.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci SFRE394:GBYN-1632-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NGR234.

Entry informationi

Entry nameiGLSA_RHISN
AccessioniPrimary (citable) accession number: C3MD81
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: June 16, 2009
Last modified: September 3, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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