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Protein

Glucokinase

Gene

glk

Organism
Rhizobium sp. (strain NGR234)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-glucose = ADP + D-glucose 6-phosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi16 – 216ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glucokinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSFRE394:GBYN-3469-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GlucokinaseUniRule annotation (EC:2.7.1.2UniRule annotation)
Alternative name(s):
Glucose kinaseUniRule annotation
Gene namesi
Name:glkUniRule annotation
Ordered Locus Names:NGR_c34850
OrganismiRhizobium sp. (strain NGR234)
Taxonomic identifieri394 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
ProteomesiUP000001054: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 339339GlucokinasePRO_1000146253Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi394.NGR_c34850.

Structurei

3D structure databases

ProteinModelPortaliC3MBY4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the bacterial glucokinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274469.
KOiK00845.
OMAiDITSHAL.
OrthoDBiEOG64BQ47.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.

Sequencei

Sequence statusi: Complete.

C3MBY4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPSASDHSFS FPILIGDIGG TNARFALLVD AASEPTQLPP VKTGDFATIE
60 70 80 90 100
DALQNGIFNK ISVRPRSAIL AVAGPIKSDE IPLTNAGWVI RPKDMLARLG
110 120 130 140 150
LEDVLVINDF EAQALAIAAP ADQDVVQIGG GSVRPRSSRV VLGPGTGLGV
160 170 180 190 200
AGLVFAQDTW IPVPGEGGHV DIGPRTERDF RIWPFLDPIE GRMAGEQILC
210 220 230 240 250
GRGIMNLYRA VCAADGVEPL FKDQAEVTTS ALSGDDPAAI ETVTLFATYL
260 270 280 290 300
GRVAGDMALV FMARGGVFLA GGISQKILPA LMRPDFRAAF EDKAPHSALM
310 320 330
RTIPTFAVVH PMAALSGLAA FARAPRDFGV AMEGRRWRS
Length:339
Mass (Da):35,896
Last modified:June 16, 2009 - v1
Checksum:iE19CA1A1EE0FE0CF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001389 Genomic DNA. Translation: ACP27209.1.
RefSeqiYP_002827962.1. NC_012587.1.

Genome annotation databases

EnsemblBacteriaiACP27209; ACP27209; NGR_c34850.
GeneIDi7792752.
KEGGirhi:NGR_c34850.
PATRICi32313521. VBIRhiSp122450_6334.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001389 Genomic DNA. Translation: ACP27209.1.
RefSeqiYP_002827962.1. NC_012587.1.

3D structure databases

ProteinModelPortaliC3MBY4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi394.NGR_c34850.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACP27209; ACP27209; NGR_c34850.
GeneIDi7792752.
KEGGirhi:NGR_c34850.
PATRICi32313521. VBIRhiSp122450_6334.

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274469.
KOiK00845.
OMAiDITSHAL.
OrthoDBiEOG64BQ47.

Enzyme and pathway databases

BioCyciSFRE394:GBYN-3469-MONOMER.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NGR234.

Entry informationi

Entry nameiGLK_RHISN
AccessioniPrimary (citable) accession number: C3MBY4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: June 16, 2009
Last modified: January 7, 2015
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.