SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

C3MBD2

- MASZ_RHISN

UniProt

C3MBD2 - MASZ_RHISN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Malate synthase G

Gene
glcB, NGR_c34110
Organism
Rhizobium sp. (strain NGR234)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA By similarity.UniRule annotation

Catalytic activityi

Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA.UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei116 – 1161Acetyl-CoA; via carbonyl oxygen By similarity
Binding sitei274 – 2741Acetyl-CoA By similarity
Binding sitei311 – 3111Acetyl-CoA By similarity
Active sitei338 – 3381Proton acceptor By similarity
Binding sitei338 – 3381Glyoxylate By similarity
Metal bindingi430 – 4301Magnesium By similarity
Binding sitei430 – 4301Glyoxylate By similarity
Metal bindingi458 – 4581Magnesium By similarity
Binding sitei539 – 5391Acetyl-CoA; via carbonyl oxygen By similarity
Active sitei629 – 6291Proton donor By similarity

GO - Molecular functioni

  1. malate synthase activity Source: UniProtKB-HAMAP
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-HAMAP
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Glyoxylate bypass, Tricarboxylic acid cycle

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

BioCyciSFRE394:GBYN-3395-MONOMER.
UniPathwayiUPA00703; UER00720.

Names & Taxonomyi

Protein namesi
Recommended name:
Malate synthase G (EC:2.3.3.9)
Gene namesi
Name:glcB
Ordered Locus Names:NGR_c34110
OrganismiRhizobium sp. (strain NGR234)
Taxonomic identifieri394 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
ProteomesiUP000001054: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 724724Malate synthase GUniRule annotationPRO_1000147427Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei615 – 6151Cysteine sulfenic acid (-SOH) By similarity

Keywords - PTMi

Oxidation

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi394.NGR_c34110.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni123 – 1242Acetyl-CoA binding By similarity
Regioni455 – 4584Glyoxylate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2225.
HOGENOMiHOG000220740.
KOiK01638.
OMAiSQFIENE.
OrthoDBiEOG6HJ286.

Family and domain databases

Gene3Di2.170.170.11. 2 hits.
HAMAPiMF_00641. Malate_synth_G.
InterProiIPR011076. Malate_synth-like.
IPR023310. Malate_synth_G_beta_sub_dom.
IPR001465. Malate_synthase.
IPR006253. Malate_synthG.
[Graphical view]
PfamiPF01274. Malate_synthase. 1 hit.
[Graphical view]
SUPFAMiSSF51645. SSF51645. 1 hit.
TIGRFAMsiTIGR01345. malate_syn_G. 1 hit.

Sequencei

Sequence statusi: Complete.

C3MBD2-1 [UniParc]FASTAAdd to Basket

« Hide

MDRVEKHDLK IDAGLHRFLV DEAMPGTGID PEHFFAALSA LVHDLAPKNR    50
ALLARRDELQ AKLDAWYREH GAPVDLDAYQ AFLKEIGYLL PEGPDFSVST 100
ANVDAEIATI AGPQLVVPVM NARYALNAAN ARWGSLYDAL YGTDAIPDAD 150
GGTRGRSYNP ARGAKVIAWA RDFLDASVPL AAGRWSDVGG LAIDGTALSL 200
TLTNGTKTTL RNPAQFAGYS GSAEAPSQIV LRQNNLHVVI VLDATTPIGQ 250
ADPAGISDII LESAITTIMD CEDSVAAVDA EDKVVVYRNW LGLMKGDLAE 300
EVAKGGRTFT RKLNADRVFT RPNGETLTLP GRALMLVRNV GHLMTNPAIL 350
DRDGREVPEG LMDAMVTALI ALHDIGANGR RANSRAGSMY VVKPKMHGPE 400
EVAFACEIFS HVEAALGLPE NTIKMGIMDE ERRTTVNLKE CIRAARDRVV 450
FINTGFLDRT GDEIHTSMEA GPMIRKGDMK QAAWIGAYEN WNVDIGLECG 500
LSGRAQIGKG MWAMPDLMAA MLEQKIAHPK AGANTAWVPS PTAATLHATH 550
YHRVDVAEVQ AGLGSRPRAR LADILSVPVA ARPNWTEEEI QRELDNNAQG 600
ILGYVVRWVD EGVGCSKVPD INNVGLMEDR ATLRISAQHM ANWLHHGIVS 650
KVQIVETMKR MAEIVDRQNA GDPSYVPMAG RLEQSIAFQA ALDLVLKGRE 700
QPNGYTEPVL HRRRLELKAK QRAS 724
Length:724
Mass (Da):78,795
Last modified:June 16, 2009 - v1
Checksum:iD90D8C146A321A1D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001389 Genomic DNA. Translation: ACP27141.1.
RefSeqiWP_012709888.1. NC_012587.1.
YP_002827894.1. NC_012587.1.

Genome annotation databases

EnsemblBacteriaiACP27141; ACP27141; NGR_c34110.
GeneIDi7792678.
KEGGirhi:NGR_c34110.
PATRICi32313365. VBIRhiSp122450_6262.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001389 Genomic DNA. Translation: ACP27141.1 .
RefSeqi WP_012709888.1. NC_012587.1.
YP_002827894.1. NC_012587.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 394.NGR_c34110.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACP27141 ; ACP27141 ; NGR_c34110 .
GeneIDi 7792678.
KEGGi rhi:NGR_c34110.
PATRICi 32313365. VBIRhiSp122450_6262.

Phylogenomic databases

eggNOGi COG2225.
HOGENOMi HOG000220740.
KOi K01638.
OMAi SQFIENE.
OrthoDBi EOG6HJ286.

Enzyme and pathway databases

UniPathwayi UPA00703 ; UER00720 .
BioCyci SFRE394:GBYN-3395-MONOMER.

Family and domain databases

Gene3Di 2.170.170.11. 2 hits.
HAMAPi MF_00641. Malate_synth_G.
InterProi IPR011076. Malate_synth-like.
IPR023310. Malate_synth_G_beta_sub_dom.
IPR001465. Malate_synthase.
IPR006253. Malate_synthG.
[Graphical view ]
Pfami PF01274. Malate_synthase. 1 hit.
[Graphical view ]
SUPFAMi SSF51645. SSF51645. 1 hit.
TIGRFAMsi TIGR01345. malate_syn_G. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NGR234.

Entry informationi

Entry nameiMASZ_RHISN
AccessioniPrimary (citable) accession number: C3MBD2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: June 16, 2009
Last modified: September 3, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi