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Protein

Trans-aconitate 2-methyltransferase

Gene

tam

Organism
Sinorhizobium fredii (strain NBRC 101917 / NGR234)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + trans-aconitate = S-adenosyl-L-homocysteine + (E)-3-(methoxycarbonyl)pent-2-enedioate.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciSFRE394:GBYN-720-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Trans-aconitate 2-methyltransferaseUniRule annotation (EC:2.1.1.144UniRule annotation)
Gene namesi
Name:tamUniRule annotation
Ordered Locus Names:NGR_c07210
OrganismiSinorhizobium fredii (strain NBRC 101917 / NGR234)
Taxonomic identifieri394 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
Proteomesi
  • UP000001054 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 257257Trans-aconitate 2-methyltransferasePRO_1000196658Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi394.NGR_c07210.

Structurei

3D structure databases

ProteinModelPortaliC3M8G8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. Tam family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107R6G. Bacteria.
COG4106. LUCA.
HOGENOMiHOG000125295.
KOiK00598.
OMAiARVDVWR.
OrthoDBiEOG6716PV.

Family and domain databases

Gene3Di1.10.150.290. 1 hit.
3.40.50.150. 1 hit.
HAMAPiMF_00560. Tran_acon_Me_trans.
InterProiIPR029063. SAM-dependent_MTases.
IPR023506. Trans-aconitate_MeTrfase.
IPR023149. Trans_acon_MeTrfase_C.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Complete.

C3M8G8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSWSAAQYVK FEDERTRPAR DLLAQVPDLP AGPAFDLGCG PGNSTQLILE
60 70 80 90 100
RFPNNPLVGI DSDENMLEAA RKRLLGLRFE RADLIGWTPP QGAALFFANA
110 120 130 140 150
VFQWLPKHID LLERLVDALV PGGTLAVQMP DNLDEPSHLL MQETAEERAF
160 170 180 190 200
AAAFSGRTIR RVPLPSPRTY VERLAPKVAR VDVWHTTYYH PLASANAIVE
210 220 230 240 250
WVKGTGLRPY LDALPANRRK DYLAAYAEKI RRAYPAMGDG RVLLRFPRLF

IVAVKAA
Length:257
Mass (Da):28,698
Last modified:June 16, 2009 - v1
Checksum:i40A128C69CF4D329
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001389 Genomic DNA. Translation: ACP24514.1.
RefSeqiWP_012707299.1. NC_012587.1.
YP_002825267.1. NC_012587.1.

Genome annotation databases

EnsemblBacteriaiACP24514; ACP24514; NGR_c07210.
GeneIDi7791947.
KEGGirhi:NGR_c07210.
PATRICi32307825. VBIRhiSp122450_3536.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001389 Genomic DNA. Translation: ACP24514.1.
RefSeqiWP_012707299.1. NC_012587.1.
YP_002825267.1. NC_012587.1.

3D structure databases

ProteinModelPortaliC3M8G8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi394.NGR_c07210.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACP24514; ACP24514; NGR_c07210.
GeneIDi7791947.
KEGGirhi:NGR_c07210.
PATRICi32307825. VBIRhiSp122450_3536.

Phylogenomic databases

eggNOGiENOG4107R6G. Bacteria.
COG4106. LUCA.
HOGENOMiHOG000125295.
KOiK00598.
OMAiARVDVWR.
OrthoDBiEOG6716PV.

Enzyme and pathway databases

BioCyciSFRE394:GBYN-720-MONOMER.

Family and domain databases

Gene3Di1.10.150.290. 1 hit.
3.40.50.150. 1 hit.
HAMAPiMF_00560. Tran_acon_Me_trans.
InterProiIPR029063. SAM-dependent_MTases.
IPR023506. Trans-aconitate_MeTrfase.
IPR023149. Trans_acon_MeTrfase_C.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NBRC 101917 / NGR234.

Entry informationi

Entry nameiTAM_SINFN
AccessioniPrimary (citable) accession number: C3M8G8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: June 16, 2009
Last modified: July 6, 2016
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.