C3LUV1 (C3LUV1_VIBCM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aminomethyltransferase RuleBase RU003981
EC=2.1.2.10 RuleBase RU003981

Gene names

Name:	gcvT EMBL ACP07256.1
Ordered Locus Names:	VCM66_A0279

Organism

Vibrio cholerae serotype O1 (strain M66-2) [Complete proteome] [HAMAP]

Taxonomic identifier

579112 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	376 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity. RuleBase RU003981
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. SAAS SAAS006223 RuleBase RU003981
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. RuleBase RU003981
Sequence similarities	Belongs to the GcvT family. RuleBase RU003980

Ontologies

Keywords
Molecular function	Aminotransferase SAAS SAAS006223 RuleBase RU003981 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: EC transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C3LUV1 [UniParc]. Last modified June 16, 2009. Version 1. Checksum: 71F698C70027DB25	FASTA	376	40,568
	10 20 30 40 50 60 MTEQHETLLT TPLHALHIEV GAKMVPFAGY DMPVQYALGV KKEHIHTREA AGLFDVSHMG 70 80 90 100 110 120 QLRLYGAQAA AALEALVPVD IIDLPVGKQR YAFFTNAQGG IMDDLMVANM GDHLFVVVNA 130 140 150 160 170 180 ACKAQDIAHL KAHLPADVEM EVIEDRALLA LQGPKAAQVL ARLQPAVAKM LFMDVQLLEI 190 200 210 220 230 240 DGAECIVSRS GYTGEDGYEI SVPADKAAAL ARKLTDFEEV EWIGLGARDS LRLECGLCLY 250 260 270 280 290 300 GHDLDPTTTP VEASLLWAIQ PVRRKGGARE GGFPGAEIIL SQIETKQVSR KRVGLIGQTK 310 320 330 340 350 360 APVREGTELF DAQGNKIGIV TSGTAGPTAD KPVSMAYVST EHAALGGEVF ADVRGKMLPM 370 TVEKMPFVPQ RYYRGA

References

[1]

"A recalibrated molecular clock and independent origins for the cholera pandemic clones." Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J., Wang W., Wang J., Qian W., Li D., Wang L. PLoS ONE 3:E4053-E4053(2008) [PubMed: 19115014] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001234 Genomic DNA. Translation: ACP07256.1.
RefSeq	YP_002811913.1. NC_012580.1.
3D structure databases
ProteinModelPortal	C3LUV1.
ModBase	Search...
Protein-protein interaction databases
STRING	C3LUV1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7781568.
GenomeReviews	Gene locus VCM66_A0279 in contig CP001234_GR.
KEGG	vcm:VCM66_A0279.
PATRIC	20069640. VBIVibCho108967_2830.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	MPVQYPL.
ProtClustDB	CLSK910129.
Family and domain databases
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. [Graphical view]
KO	K00605.
PANTHER	PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. GcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C3LUV1_VIBCM

Accession

Primary (citable) accession number: C3LUV1

Entry history

Integrated into UniProtKB/TrEMBL:	June 16, 2009
Last sequence update:	June 16, 2009
Last modified:	December 14, 2011
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)