SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

C3LUC2

- PNCB_VIBCM

UniProt

C3LUC2 - PNCB_VIBCM

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Nicotinate phosphoribosyltransferase
Gene
pncB, VCM66_A0096
Organism
Vibrio cholerae serotype O1 (strain M66-2)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity.UniRule annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ligase activity Source: UniProtKB-KW
  2. nicotinate phosphoribosyltransferase activity Source: InterPro
  3. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro

GO - Biological processi

  1. NAD biosynthetic process Source: UniProtKB-UniPathway
  2. nicotinate nucleotide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesis

Enzyme and pathway databases

BioCyciVCHO579112:GJAW-2875-MONOMER.
UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferase (EC:6.3.4.21)
Short name:
NAPRTase
Gene namesi
Name:pncB
Ordered Locus Names:VCM66_A0096
OrganismiVibrio cholerae serotype O1 (strain M66-2)
Taxonomic identifieri579112 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000001217: Chromosome II

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 435435Nicotinate phosphoribosyltransferaseUniRule annotation
PRO_1000191533Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi579112.VCM66_A0096.

Structurei

3D structure databases

ProteinModelPortaliC3LUC2.

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.

Phylogenomic databases

eggNOGiCOG1488.
HOGENOMiHOG000284928.
KOiK00763.
OMAiQAVFHRY.
OrthoDBiEOG6X10XB.

Family and domain databases

HAMAPiMF_00570. NAPRTase.
InterProiIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

C3LUC2-1 [UniParc]FASTAAdd to Basket

« Hide

MNPRLFSPHI IRSLLDLDAY KINMMQAIHH FYPDVSVRYE LIVRSEEDAS    50
GLLDAIRQEI AHLGTLRFSD ADIHYLTQHA PHLKATFLQS LRYFHFVPQE 100
QVEMGIVKQG GKQQLRISIR GSWRDTILYE TLVMAIVSEV RSRQRWAEVP 150
ADLPLKVLKT KLDQLKAEIE RRGINNFSLT EMGTRRRFSS QVQRDVLACL 200
KQEIPQWVLG TSNYHFAREF DLKPIGTIAH EWFMGHQALV NERDSQQVAL 250
ERWLTAFDGM LAIAPTDTLT IDAFLNDFNR HLANAYDGVR HDSGCPFRWG 300
DKMIAHYQQL GIDPTTKLFI FSDGLDFDQA LELCEYFAGR VKISFGIGTF 350
LTNDLANWRN AAGVEYRPLS IVIKLAECQG RPVAKISDQP EKAMCEDPIF 400
LANLKRRFNI ELDVDALIQE LRHQKRSPRH YISAA 435
Length:435
Mass (Da):50,078
Last modified:June 16, 2009 - v1
Checksum:i2CEF5D950C6C11FE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001234 Genomic DNA. Translation: ACP07077.1.
RefSeqiYP_002811734.1. NC_012580.1.

Genome annotation databases

EnsemblBacteriaiACP07077; ACP07077; VCM66_A0096.
GeneIDi7781389.
KEGGivcm:VCM66_A0096.
PATRICi20069296. VBIVibCho108967_2658.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001234 Genomic DNA. Translation: ACP07077.1 .
RefSeqi YP_002811734.1. NC_012580.1.

3D structure databases

ProteinModelPortali C3LUC2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 579112.VCM66_A0096.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACP07077 ; ACP07077 ; VCM66_A0096 .
GeneIDi 7781389.
KEGGi vcm:VCM66_A0096.
PATRICi 20069296. VBIVibCho108967_2658.

Phylogenomic databases

eggNOGi COG1488.
HOGENOMi HOG000284928.
KOi K00763.
OMAi QAVFHRY.
OrthoDBi EOG6X10XB.

Enzyme and pathway databases

UniPathwayi UPA00253 ; UER00457 .
BioCyci VCHO579112:GJAW-2875-MONOMER.

Family and domain databases

HAMAPi MF_00570. NAPRTase.
InterProi IPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view ]
PANTHERi PTHR11098. PTHR11098. 1 hit.
Pfami PF04095. NAPRTase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000484. NAPRT. 1 hit.
SUPFAMi SSF51690. SSF51690. 1 hit.
TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "A recalibrated molecular clock and independent origins for the cholera pandemic clones."
    Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J., Wang W., Wang J., Qian W., Li D., Wang L.
    PLoS ONE 3:E4053-E4053(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: M66-2.

Entry informationi

Entry nameiPNCB_VIBCM
AccessioniPrimary (citable) accession number: C3LUC2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: June 16, 2009
Last modified: September 3, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi