C3LR51 (C3LR51_VIBCM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aspartate carbamoyltransferase HAMAP MF_00001
EC=2.1.3.2 HAMAP MF_00001

Alternative name(s):
Aspartate transcarbamylase HAMAP MF_00001

Gene names

Name:	pyrB HAMAP MF_00001 EMBL ACP06729.1
Ordered Locus Names:	VCM66_2432

Organism

Vibrio cholerae serotype O1 (strain M66-2) [Complete proteome] [HAMAP]

Taxonomic identifier

579112 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	330 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate. HAMAP MF_00001
Pathway	Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3. HAMAP MF_00001
Sequence similarities	Belongs to the ATCase/OTCase family. HAMAP MF_00001 RuleBase RU003634

Ontologies

Keywords
Biological process	Pyrimidine biosynthesis HAMAP MF_00001
Molecular function	Transferase HAMAP MF_00001 RuleBase RU003634 EMBL ACP06729.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	'de novo' pyrimidine base biosynthetic process Inferred from electronic annotation. Source: InterPro cellular amino acid metabolic process Inferred from electronic annotation. Source: InterPro pyrimidine nucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	amino acid binding Inferred from electronic annotation. Source: InterPro aspartate carbamoyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C3LR51 [UniParc]. Last modified June 16, 2009. Version 1. Checksum: E3556D0CD954BEAE	FASTA	330	36,759
	10 20 30 40 50 60 MLKPPLWGAF LWLLENIGKT IMANSLYQKH IISIAELSRA ELELIVKTAG QLKAQPNPEL 70 80 90 100 110 120 IKHKVVASCF FEPSTRTRLS FETAIQRIGG SVIGFDNGGN TSLAKKGETL ADSVRVISSY 130 140 150 160 170 180 VDAFVMRHPQ EGAARLASEF SNGVPVINAG DGSNQHPSQT LLDLYSIFET QGRLDNLDVA 190 200 210 220 230 240 FVGDLKYGRT VHSLAQALAK FDNNRFYFVA PEALAMPDYI CEELDEAGVK YQVFSDMESV 250 260 270 280 290 300 IPELDILYMT RVQKERFDES EYAHIKSAYI LTAAHLSDAR SNLKVLHPLP RVDEITTDVD 310 320 330 KTPHAYYFEQ VENGVYAREA LLALVLNESL

References

[1]

"A recalibrated molecular clock and independent origins for the cholera pandemic clones." Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J., Wang W., Wang J., Qian W., Li D., Wang L. PLoS ONE 3:E4053-E4053(2008) [PubMed: 19115014] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001233 Genomic DNA. Translation: ACP06729.1.
RefSeq	YP_002811180.1. NC_012578.1.
3D structure databases
ProteinModelPortal	C3LR51.
SMR	C3LR51. Positions 23-330.
ModBase	Search...
Protein-protein interaction databases
STRING	C3LR51.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7773690.
GenomeReviews	Gene locus VCM66_2432 in contig CP001233_GR.
KEGG	vcm:VCM66_2432.
PATRIC	20068590. VBIVibCho108967_2313.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	FKQSFYG.
ProtClustDB	PRK00856.
Family and domain databases
HAMAP	MF_00001. Asp_carb_tr. [Tree]
InterPro	IPR006132. Asp/Orn_carbamoyltranf_P-bd. IPR006130. Asp/Orn_carbamoylTrfase. IPR006131. Asp_carbamoyltransf_Asp/Orn-bd. IPR002082. Asp_carbamoyltransf_euk. [Graphical view]
KO	K00609.
Pfam	PF00185. OTCace. 1 hit. PF02729. OTCace_N. 1 hit. [Graphical view]
PRINTS	PR00100. AOTCASE. PR00101. ATCASE.
SUPFAM	SSF53671. Asp/Orn_carbamoyltranf. 1 hit.
TIGRFAMs	TIGR00670. Asp_carb_tr. 1 hit.
PROSITE	PS00097. CARBAMOYLTRANSFERASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C3LR51_VIBCM

Accession

Primary (citable) accession number: C3LR51

Entry history

Integrated into UniProtKB/TrEMBL:	June 16, 2009
Last sequence update:	June 16, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)