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Protein

Glycogen synthase

Gene

glgA

Organism
Vibrio cholerae serotype O1 (strain M66-2)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei18 – 181ADP-glucoseUniRule annotation

GO - Molecular functioni

  1. starch synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciVCHO579112:GJAW-1729-MONOMER.
UniPathwayiUPA00164.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:VCM66_1666
OrganismiVibrio cholerae serotype O1 (strain M66-2)
Taxonomic identifieri579112 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000001217: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 484484Glycogen synthasePRO_1000190091Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi579112.VCM66_1666.

Structurei

3D structure databases

ProteinModelPortaliC3LN49.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiNLQINGM.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

C3LN49-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEQFNVWFTV SEVQGLVKSG GLADVAKALP QALKALHQQV AIALPAYRSV
60 70 80 90 100
PGKEDAELVL ETELTHWPHT QYRVLKRDLD GVPIYLIDCP AYFDRPALYA
110 120 130 140 150
ENNQAYADNG ERFGFFSAAC LDVLPKLGIQ PDIIHANDWH TGLVPFLLKT
160 170 180 190 200
RYRYDSFFEQ VKSVLTVHNA IFKGIFSYHQ LEVIPELNLS GMEFLQYGHD
210 220 230 240 250
HVSMLRAGIA FADKVNAVSP NYAAELLTPL GAHGLVDDFV RRARDLHGIV
260 270 280 290 300
NGCDYSEWNP RTDHYLPATY SDEPESMRKG KALCKTALQE ELHLPVTDVP
310 320 330 340 350
LFGMVCRLTH QKGFHYLLPI LEQFLRNNVQ VVIVGTGEPE VAARLNKIAH
360 370 380 390 400
YHRAKFAFVE TYSERLAHWV EAGSDFFLMP SEFEACGLNQ IYSMAYGTLP
410 420 430 440 450
IVREVGGLKD TVNDYDKFPE RATGFGYQEP TPEALLITMQ RALLFYLQQP
460 470 480
EEMLKVQQRA MQQNFSWEES AQEYMKMYRL ARFG
Length:484
Mass (Da):55,067
Last modified:June 16, 2009 - v1
Checksum:i776D1D3E6BCC0920
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001233 Genomic DNA. Translation: ACP05975.1.
RefSeqiYP_002810426.1. NC_012578.1.

Genome annotation databases

EnsemblBacteriaiACP05975; ACP05975; VCM66_1666.
GeneIDi7772936.
KEGGivcm:VCM66_1666.
PATRICi20067084. VBIVibCho108967_1590.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001233 Genomic DNA. Translation: ACP05975.1.
RefSeqiYP_002810426.1. NC_012578.1.

3D structure databases

ProteinModelPortaliC3LN49.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi579112.VCM66_1666.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACP05975; ACP05975; VCM66_1666.
GeneIDi7772936.
KEGGivcm:VCM66_1666.
PATRICi20067084. VBIVibCho108967_1590.

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiNLQINGM.
OrthoDBiEOG6JTC6Z.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciVCHO579112:GJAW-1729-MONOMER.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "A recalibrated molecular clock and independent origins for the cholera pandemic clones."
    Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J., Wang W., Wang J., Qian W., Li D., Wang L.
    PLoS ONE 3:E4053-E4053(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: M66-2.

Entry informationi

Entry nameiGLGA_VIBCM
AccessioniPrimary (citable) accession number: C3LN49
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: June 16, 2009
Last modified: January 7, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.