C3LLN6 (C3LLN6_VIBCM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative phosphoribosylaminoimidazole-succinocarboxamide synthase EMBL ACP05462.1
EC=6.3.2.6 EMBL ACP05462.1

Gene names

Ordered Locus Names:

VCM66_1145

Organism

Vibrio cholerae serotype O1 (strain M66-2) [Complete proteome] [HAMAP]

Taxonomic identifier

579112 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	405 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate. SAAS SAAS018236
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2. SAAS SAAS018236
Sequence similarities	Belongs to the SAICAR synthetase family. RuleBase RU004193

Ontologies

Keywords
Biological process	Purine biosynthesis SAAS SAAS018236
Ligand	ATP-binding SAAS SAAS018236 Nucleotide-binding
Molecular function	Ligase SAAS SAAS018236 EMBL ACP05462.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	purine nucleotide biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoribosylaminoimidazolesuccinocarboxamide synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C3LLN6 [UniParc]. Last modified June 16, 2009. Version 1. Checksum: FDD730F43A28CD71	FASTA	405	45,799
	10 20 30 40 50 60 MLFVWQHKLV LVSCAQPAVF HSAKSLKRCL NSDRNVSMSL ADQVLAVNDD LPIRTHQPVH 70 80 90 100 110 120 SGKVRSVYWL TEQDSRRLIK EKGYPVAEDA PLAIMVISDR ISAFDCIWHA EGGVHGVPGK 130 140 150 160 170 180 GAALNAISNH WFKLFKQHGL AESHILDIPH PFVWIVQKAR PIKIEAICRQ YITGSMWRAY 190 200 210 220 230 240 AKGEREFCGI TLPEGLEKDS QLPELLMTPS TKGILRGIPG VPEADDVNIS RQDIEANYAA 250 260 270 280 290 300 FNFNQPQDID HYETLLKQGF AVISEALKSV GQLFVDTKFE FGYVADQQGQ QKLIYMDEVG 310 320 330 340 350 360 TPDSSRIWDA QQYQQGKIVE NSKEGFRQFL LNYFPDPDIL LNKDRMPERE ALARDNALPL 370 380 390 400 EALMDISRTY LGIAEKITGQ PIHLSHQPKQ EIIAILDKEY GLIER

References

[1]

"A recalibrated molecular clock and independent origins for the cholera pandemic clones." Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J., Wang W., Wang J., Qian W., Li D., Wang L. PLoS ONE 3:E4053-E4053(2008) [PubMed: 19115014] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001233 Genomic DNA. Translation: ACP05462.1.
RefSeq	YP_002809913.1. NC_012578.1.
3D structure databases
ProteinModelPortal	C3LLN6.
ModBase	Search...
Protein-protein interaction databases
STRING	C3LLN6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7772423.
GenomeReviews	Gene locus VCM66_1145 in contig CP001233_GR.
KEGG	vcm:VCM66_1145.
PATRIC	20066079. VBIVibCho108967_1094.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	SSRIWDG.
ProtClustDB	PRK13960.
Family and domain databases
HAMAP	MF_00137. SAICAR_synth. [Tree]
InterPro	IPR013816. ATP_grasp_subdomain_2. IPR014106. PurC_vibrio. IPR001636. SAICAR_synth. IPR018236. SAICAR_synthetase_CS. [Graphical view]
Gene3D	G3DSA:3.30.470.20. ATP_grasp_subdomain_2. 1 hit.
KO	K01923.
PANTHER	PTHR11609. SAICAR_synt. 1 hit.
Pfam	PF01259. SAICAR_synt. 1 hit. [Graphical view]
TIGRFAMs	TIGR02735. PurC_vibrio. 1 hit.
PROSITE	PS01057. SAICAR_SYNTHETASE_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C3LLN6_VIBCM

Accession

Primary (citable) accession number: C3LLN6

Entry history

Integrated into UniProtKB/TrEMBL:	June 16, 2009
Last sequence update:	June 16, 2009
Last modified:	December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)