C3LJ70 (RL1_BACAC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L1

Gene names

Name:	rplA
Ordered Locus Names:	BAMEG_0113

Organism

Bacillus anthracis (strain CDC 684 / NRRL 3495) [Complete proteome] [HAMAP]

Taxonomic identifier

568206 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group › Bacillus anthracis

Protein attributes

Sequence length	230 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release By similarity. HAMAP-Rule MF_01318 Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA By similarity. HAMAP-Rule MF_01318
Subunit structure	Part of the 50S ribosomal subunit By similarity.
Sequence similarities	Belongs to the ribosomal protein L1P family.

Ontologies

Keywords
Biological process	Translation regulation
Ligand	RNA-binding rRNA-binding tRNA-binding
Molecular function	Repressor Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	regulation of translation Inferred from electronic annotation. Source: UniProtKB-KW translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	large ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular_function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro tRNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 230	230	50S ribosomal protein L1 HAMAP-Rule MF_01318		PRO_1000165657

Sequences

	Sequence		Length	Mass (Da)
	C3LJ70 [UniParc]. Last modified June 16, 2009. Version 1. Checksum: 69D8245046A64636	FASTA	230	24,481
	10 20 30 40 50 60 MAKRGKKYVE AAKLVDRAAA YSATEAVELV KKTNTAKFDA TVEAAFRLGV DPKKADQQIR 70 80 90 100 110 120 GAVVLPHGTG KVQRVLVFAK GEKAKEAEAA GADFVGDADY IGKIQQGWFD FDVVVATPDM 130 140 150 160 170 180 MGEVGKLGRV LGPKGLMPNP KTGTVTFDVT KAVNEIKAGK VEYRVDKAGN IHVPIGKVSF 190 200 210 220 230 EDAKLVENFR TIADTLQKVK PAAAKGTYMK NVTVASTMGP GVRVDVSTLA

References

[1]	"Genome sequence of Bacillus anthracis str. CDC 684." Dodson R.J., Munk A.C., Brettin T., Bruce D., Detter C., Tapia R., Han C., Sutton G., Sims D. Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CDC 684 / NRRL 3495.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001215 Genomic DNA. Translation: ACP13948.1.
RefSeq	YP_002812780.1. NC_012581.1.
3D structure databases
ProteinModelPortal	C3LJ70.
SMR	C3LJ70. Positions 6-227.
ModBase	Search...
Protein-protein interaction databases
STRING	568206.BAMEG_0113.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACP13948; ACP13948; BAMEG_0113.
GeneID	7783319.
KEGG	bah:BAMEG_0113.
PATRIC	18789954. VBIBacAnt127120_0402.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0081.
HOGENOM	HOG000207015.
KO	K02863.
OMA	AKGRYVK.
ProtClustDB	PRK05424.
Enzyme and pathway databases
BioCyc	BANT568206:GHVT-1867-MONOMER.
Family and domain databases
Gene3D	3.30.190.20. 2 hits. 3.40.50.790. 1 hit.
HAMAP	MF_01318_B. Ribosomal_L1_B.
InterPro	IPR005878. Ribosom_L1_bac-type. IPR002143. Ribosomal_L1. IPR016094. Ribosomal_L1_2-a/b-sand. IPR016095. Ribosomal_L1_3-a/b-sand. IPR023673. Ribosomal_L1_CS. IPR023674. Ribosomal_L1_SF. [Graphical view]
Pfam	PF00687. Ribosomal_L1. 1 hit. [Graphical view]
PIRSF	PIRSF002155. Ribosomal_L1. 1 hit.
SUPFAM	SSF56808. Ribosomal_L1. 1 hit.
TIGRFAMs	TIGR01169. rplA_bact. 1 hit.
PROSITE	PS01199. RIBOSOMAL_L1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL1_BACAC

Accession

Primary (citable) accession number: C3LJ70

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	June 16, 2009
Last modified:	May 1, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program