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C3L507 (CH60_BACAC) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
60 kDa chaperonin
Alternative name(s):
GroEL protein
Protein Cpn60
Gene names
Name:groL
Synonyms:groEL
Ordered Locus Names:BAMEG_0312
OrganismBacillus anthracis (strain CDC 684 / NRRL 3495) [Complete proteome] [HAMAP]
Taxonomic identifier568206 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group ›

Protein attributes

Sequence length544 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions By similarity. HAMAP-Rule MF_00600

Subunit structure

Oligomer of 14 subunits composed of two stacked rings of 7 subunits By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00600.

Sequence similarities

Belongs to the chaperonin (HSP60) family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionChaperone
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processprotein refolding

Inferred from electronic annotation. Source: HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 54454460 kDa chaperonin HAMAP-Rule MF_00600
PRO_1000147014

Sequences

Sequence LengthMass (Da)Tools
C3L507 [UniParc].

Last modified June 16, 2009. Version 1.
Checksum: 3F05EEBE9946DD31

FASTA54457,432
        10         20         30         40         50         60 
MAKDIKFSEE ARRSMLRGVD TLANAVKVTL GPKGRNVVLE KKFGSPLITN DGVTIAKEIE 

        70         80         90        100        110        120 
LEDAFENMGA KLVAEVASKT NDVAGDGTTT ATVLAQAMIR EGLKNVTAGA NPMGLRKGIE 

       130        140        150        160        170        180 
KAVVAAVEEL KTISKPIEGK SSIAQVAAIS AADEEVGQLI AEAMERVGND GVITLEESKG 

       190        200        210        220        230        240 
FTTELDVVEG MQFDRGYASP YMITDSDKME AVLDNPYILI TDKKISNIQE ILPVLEQVVQ 

       250        260        270        280        290        300 
QGKPLLIIAE DVEGEALATL VVNKLRGTFN VVAVKAPGFG DRRKAMLEDI AILTGGEVIT 

       310        320        330        340        350        360 
EELGRDLKSA TVESLGRAGK VVVTKENTTV VEGVGSTEQI EARIGQIRAQ LEETTSEFDR 

       370        380        390        400        410        420 
EKLQERLAKL VGGVAVIKVG AATETELKER KLRIEDALNS TRAAVEEGIV AGGGTSLMNV 

       430        440        450        460        470        480 
YTKVASIVAE GDEATGINIV LRALEEPVRQ IAINAGLEGS VVVERLKGEK VGVGFNAATG 

       490        500        510        520        530        540 
EWVNMLETGI VDPAKVTRSA LQNAASVAAM FLTTEAVVAD KPEPNAPAMP DMGGMGMGGM 


GGMM

« Hide

References

[1]"Genome sequence of Bacillus anthracis str. CDC 684."
Dodson R.J., Munk A.C., Brettin T., Bruce D., Detter C., Tapia R., Han C., Sutton G., Sims D.
Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CDC 684 / NRRL 3495.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001215 Genomic DNA. Translation: ACP15006.1.
RefSeqYP_002812943.1. NC_012581.1.

3D structure databases

ProteinModelPortalC3L507.
SMRC3L507. Positions 2-523.
ModBaseSearch...

Protein-protein interaction databases

STRING568206.BAMEG_0312.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACP15006; ACP15006; BAMEG_0312.
GeneID7786114.
KEGGbah:BAMEG_0312.
PATRIC18790347. VBIBacAnt127120_0569.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0459.
HOGENOMHOG000076290.
KOK04077.
OMAWVNMLES.
ProtClustDBPRK00013.

Enzyme and pathway databases

BioCycBANT568206:GHVT-302-MONOMER.

Family and domain databases

Gene3D1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPMF_00600. CH60.
InterProIPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
[Graphical view]
PANTHERPTHR11353. PTHR11353. 1 hit.
PfamPF00118. Cpn60_TCP1. 1 hit.
[Graphical view]
PRINTSPR00298. CHAPERONIN60.
SUPFAMSSF48592. GroEL-ATPase. 1 hit.
SSF52029. SSF52029. 1 hit.
TIGRFAMsTIGR02348. GroEL. 1 hit.
PROSITEPS00296. CHAPERONINS_CPN60. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCH60_BACAC
AccessionPrimary (citable) accession number: C3L507
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: June 16, 2009
Last modified: May 29, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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