Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Adenine deaminase

Gene

ade

Organism
Clostridium botulinum (strain 657 / Type Ba4)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Manganese

Enzyme and pathway databases

BioCyciCBOT515621:GCP3-339-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminaseUniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
AdenaseUniRule annotation
Short name:
Adenine aminaseUniRule annotation
Gene namesi
Name:adeUniRule annotation
Ordered Locus Names:CLJ_B0349
OrganismiClostridium botulinum (strain 657 / Type Ba4)
Taxonomic identifieri515621 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 599599Adenine deaminasePRO_1000215358Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliC3KZB6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the adenine deaminase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000276949.
KOiK01486.
OMAiCTDDKHL.
OrthoDBiEOG622PNM.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.

Sequencei

Sequence statusi: Complete.

C3KZB6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFNKFNTKPL WEVSKTLSSV AQGFEPADMV IINSRLINVC TREVIENTDV
60 70 80 90 100
AISCGRIALV GDAKHCIGES TEVIDAKGQY IAPGFLDGHI HVESSMLSVS
110 120 130 140 150
EYARSVVPHG TVGIYMDPHE ICNVLGLNGV RYMIEDGKGT PLKNMVTTPS
160 170 180 190 200
CVPAVPGFED TGAAVGPEDV RETMKWDEIV GLGEMMNFPG ILYSTDHAHG
210 220 230 240 250
VVGETLKASK TVTGHYSLPE TGKGLNGYIA SGVRCCHEST RAEDALAKMR
260 270 280 290 300
LGMYAMFREG SAWHDLKEVS KAITENKVDS RFAVLISDDT HPHTLLKDGH
310 320 330 340 350
LDHIIKRAIE EGIEPLTAIQ MVTINCAQCF QMDHELGSIT PGKCADIVLI
360 370 380 390 400
EDLKDVKITK VIIDGNLVAK DGVLTTSIAK YDYPEDAMHS MHIKDKITPA
410 420 430 440 450
SFNIMAQNKE KVTTRVIEII PERVGTYERH IELNVKDDKV QCDPSKDVLK
460 470 480 490 500
AVVFERHHET GKAGYGFVKG FGIKRGAMAA TVAHDAHNLL VIGTNDEDMA
510 520 530 540 550
LAANTLIECG GGMVAVQDGK VLGLVPLPIA GLMSNKPLEE MAEMVEKLDS
560 570 580 590
AWKEIGCDIV SPFMTMALIP LACLPELRLT NRGLVDCNKF EFVSLFIEE
Length:599
Mass (Da):65,348
Last modified:June 16, 2009 - v1
Checksum:i245CA1460EC26D4B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001083 Genomic DNA. Translation: ACQ52836.1.
RefSeqiWP_003360406.1. NC_012658.1.

Genome annotation databases

EnsemblBacteriaiACQ52836; ACQ52836; CLJ_B0349.
KEGGicbi:CLJ_B0349.
PATRICi19409131. VBICloBot19908_0604.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001083 Genomic DNA. Translation: ACQ52836.1.
RefSeqiWP_003360406.1. NC_012658.1.

3D structure databases

ProteinModelPortaliC3KZB6.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACQ52836; ACQ52836; CLJ_B0349.
KEGGicbi:CLJ_B0349.
PATRICi19409131. VBICloBot19908_0604.

Phylogenomic databases

HOGENOMiHOG000276949.
KOiK01486.
OMAiCTDDKHL.
OrthoDBiEOG622PNM.

Enzyme and pathway databases

BioCyciCBOT515621:GCP3-339-MONOMER.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Clostridium botulinum Ba4 strain 657."
    Shrivastava S., Brown J.L., Bruce D., Detter C., Munk C., Smith L.A., Smith T.J., Sutton G., Brettin T.S.
    Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 657 / Type Ba4.

Entry informationi

Entry nameiADEC_CLOB6
AccessioniPrimary (citable) accession number: C3KZB6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: June 16, 2009
Last modified: November 11, 2015
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.