SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

C3KV31

- C3KV31_CLOB6

UniProt

C3KV31 - C3KV31_CLOB6

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Alanine racemase
Gene
alr, CLJ_B3701
Organism
Clostridium botulinum (strain 657 / Type Ba4)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei38 – 381Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei136 – 1361Substrate By similarityUniRule annotation
Active sitei267 – 2671Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei315 – 3151Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciCBOT515621:GCP3-3657-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alrImported
Ordered Locus Names:CLJ_B3701Imported
OrganismiClostridium botulinum (strain 657 / Type Ba4)Imported
Taxonomic identifieri515621 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000002333: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei38 – 381N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi515621.CLJ_B3701.

Structurei

3D structure databases

ProteinModelPortaliC3KV31.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031444.
KOiK01775.
OMAiWRDMARR.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C3KV31-1 [UniParc]FASTAAdd to Basket

« Hide

MFRNLRAVWA EIDLDNLQHN LKQIKKICGN KEIIGVIKAN AYGHGAMEIA    50
PTLLENGVSR LAVAVLSEAM ELRMSGVKNP IMILGYTPWA LGDMLLDNDI 100
EQSVYSYNDA LELSKIAVLK RKILKIHIVV DTGMGRIGFL PTKESVEDVY 150
KISKLPNIEI EGVFSHFSSA DELDKDYTLY QMNKYNEFIN KLEEKNIQLP 200
IKHIANSAAI IDLENTHLDA VRAGIIMYGY YPSNYVLRNN INLKPVMSLK 250
TSIVHIKKVS SGEYISYGRT FKTKRESIIA TLPIGYADGY NRLLSNKGKV 300
IVNGKLAPVI GRVCMDQCMI DVTFIENLKV GDVVTIMGEE NGVSYTAEDI 350
ASQIGTISYE VICNVNKRVP RVYKKDGKII NVVNYI 386
Length:386
Mass (Da):43,244
Last modified:June 16, 2009 - v1
Checksum:i5D90B89D7985946D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001083 Genomic DNA. Translation: ACQ52049.1.
RefSeqiWP_003360266.1. NC_012658.1.
YP_002864409.1. NC_012658.1.

Genome annotation databases

EnsemblBacteriaiACQ52049; ACQ52049; CLJ_B3701.
GeneIDi7880028.
KEGGicbi:CLJ_B3701.
PATRICi19415713. VBICloBot19908_3855.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001083 Genomic DNA. Translation: ACQ52049.1 .
RefSeqi WP_003360266.1. NC_012658.1.
YP_002864409.1. NC_012658.1.

3D structure databases

ProteinModelPortali C3KV31.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 515621.CLJ_B3701.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACQ52049 ; ACQ52049 ; CLJ_B3701 .
GeneIDi 7880028.
KEGGi cbi:CLJ_B3701.
PATRICi 19415713. VBICloBot19908_3855.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031444.
KOi K01775.
OMAi WRDMARR.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci CBOT515621:GCP3-3657-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Clostridium botulinum Ba4 strain 657."
    Shrivastava S., Brown J.L., Bruce D., Detter C., Munk C., Smith L.A., Smith T.J., Sutton G., Brettin T.S.
    Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 657 / Type Ba4.

Entry informationi

Entry nameiC3KV31_CLOB6
AccessioniPrimary (citable) accession number: C3KV31
Entry historyi
Integrated into UniProtKB/TrEMBL: June 16, 2009
Last sequence update: June 16, 2009
Last modified: September 3, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi