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C3KU84 (PYRF_CLOB6) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Orotidine 5'-phosphate decarboxylase

EC=4.1.1.23
Alternative name(s):
OMP decarboxylase
Short name=OMPDCase
Short name=OMPdecase
Gene names
Name:pyrF
Ordered Locus Names:CLJ_B3511
OrganismClostridium botulinum (strain 657 / Type Ba4) [Complete proteome] [HAMAP]
Taxonomic identifier515621 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

Protein attributes

Sequence length283 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processPyrimidine biosynthesis
   Molecular functionDecarboxylase
Lyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_process'de novo' UMP biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

'de novo' pyrimidine nucleobase biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionorotidine-5'-phosphate decarboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 283283Orotidine 5'-phosphate decarboxylase HAMAP-Rule MF_01215
PRO_1000213891

Sites

Active site971Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
C3KU84 [UniParc].

Last modified June 16, 2009. Version 1.
Checksum: C101A057314FD643

FASTA28331,786
        10         20         30         40         50         60 
MIIDKLYENV EKKGCVCVGL DTDISYLPKG FLNKFTNIED AIFAFNQRIV DSTFDVSACY 

        70         80         90        100        110        120 
KVQIAYYEAM GIKGMILYKK TLEYIRKKGG IVIADIKRGD ISATAKMYAK AHFEGDFESD 

       130        140        150        160        170        180 
FITLNPYMGM DTLEPYKDYF KNKEKGVFLL LRTSNEGSKD IQYLDLKDNK KVYNKVGEKI 

       190        200        210        220        230        240 
ENIGKEFLGN CGYSSIGAVV GCTAEENNIR KELKHTFFLI PGYGAQGGKA EVAKSYLSGG 

       250        260        270        280 
NGGIVNSSRG ILLAYKKYDE EGKNFEECAR NEVINMKKTL QII 

« Hide

References

[1]"Genome sequence of Clostridium botulinum Ba4 strain 657."
Shrivastava S., Brown J.L., Bruce D., Detter C., Munk C., Smith L.A., Smith T.J., Sutton G., Brettin T.S.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 657 / Type Ba4.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001083 Genomic DNA. Translation: ACQ54815.1.
RefSeqYP_002864246.1. NC_012658.1.

3D structure databases

ProteinModelPortalC3KU84.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING515621.CLJ_B3511.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACQ54815; ACQ54815; CLJ_B3511.
GeneID7881281.
KEGGcbi:CLJ_B3511.
PATRIC19415337. VBICloBot19908_3690.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0284.
HOGENOMHOG000245747.
KOK01591.
OMADATHHLC.
OrthoDBEOG6DZF33.

Enzyme and pathway databases

BioCycCBOT515621:GCP3-3470-MONOMER.
UniPathwayUPA00070; UER00120.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_01215. OMPdecase_type2.
InterProIPR013785. Aldolase_TIM.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
TIGRFAMsTIGR02127. pyrF_sub2. 1 hit.
ProtoNetSearch...

Entry information

Entry namePYRF_CLOB6
AccessionPrimary (citable) accession number: C3KU84
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: June 16, 2009
Last modified: May 14, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways