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C3KDD6 (C3KDD6_PSEFS) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddlB EMBL CAY47215.1
Synonyms:ddl HAMAP-Rule MF_00047
Ordered Locus Names:PFLU_0949 EMBL CAY47215.1
OrganismPseudomonas fluorescens (strain SBW25) [Complete proteome] [HAMAP] EMBL CAY47215.1
Taxonomic identifier216595 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length318 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011095

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011095.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011095

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain116 – 311196ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding142 – 19756ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2651Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2781Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2781Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2801Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
C3KDD6 [UniParc].

Last modified June 16, 2009. Version 1.
Checksum: 7A0C8244D2D1D576

FASTA31833,891
        10         20         30         40         50         60 
MTTDYGSLFS TITPADFGRV AVLFGGKSAE REVSLKSGNA VLEALQSAGV NAFGIDVGDD 

        70         80         90        100        110        120 
FLARLQAEKI DRAFIILHGR GGEDGSMQGL LECAGIPYTG SGILASALAM DKLRTKQVWH 

       130        140        150        160        170        180 
SLGIPTPRHS VLCSEDDCIS AAKELGLPLI VKPAHEGSSI GMAKVNSAAE LIDAWKAAST 

       190        200        210        220        230        240 
YDSQVLVEQW IQGPEYTIAT LRGQVLPPIA LGTPHTFYDY DAKYVASDTQ YRIPCGLDAT 

       250        260        270        280        290        300 
KEQELMDLTA KACEALGIAG WARADVMQDD QGNFWFLEVN TAPGMTDHSL VPMAARAAGL 

       310 
DFQQLVLAIL AASIEPRG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM181176 Genomic DNA. Translation: CAY47215.1.
RefSeqYP_002870611.1. NC_012660.1.

3D structure databases

ProteinModelPortalC3KDD6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING216595.PFLU0949.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAY47215; CAY47215; PFLU_0949.
GeneID7817815.
KEGGpfs:PFLU0949.
PATRIC19896134. VBIPseFlu98510_1185.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1181.
KOK01921.
OMAEDPARES.
OrthoDBEOG6ND0KB.

Enzyme and pathway databases

UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC3KDD6_PSEFS
AccessionPrimary (citable) accession number: C3KDD6
Entry history
Integrated into UniProtKB/TrEMBL: June 16, 2009
Last sequence update: June 16, 2009
Last modified: June 11, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)