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C3KAH3

- SYR_PSEFS

UniProt

C3KAH3 - SYR_PSEFS

Protein

Arginine--tRNA ligase

Gene

argS

Organism
Pseudomonas fluorescens (strain SBW25)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 36 (01 Oct 2014)
      Sequence version 1 (16 Jun 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

    GO - Molecular functioni

    1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
    2. ATP binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Aminoacyl-tRNA synthetase, Ligase

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
    Alternative name(s):
    Arginyl-tRNA synthetaseUniRule annotation
    Short name:
    ArgRSUniRule annotation
    Gene namesi
    Name:argSUniRule annotation
    Ordered Locus Names:PFLU_0401
    OrganismiPseudomonas fluorescens (strain SBW25)
    Taxonomic identifieri216595 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000002332: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 578578Arginine--tRNA ligasePRO_1000203102Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi216595.PFLU0401.

    Structurei

    3D structure databases

    ProteinModelPortaliC3KAH3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi127 – 13711"HIGH" regionAdd
    BLAST

    Sequence similaritiesi

    Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0018.
    KOiK01887.
    OMAiMEHMGFG.
    OrthoDBiEOG6JB13C.

    Family and domain databases

    Gene3Di1.10.730.10. 1 hit.
    3.30.1360.70. 1 hit.
    3.40.50.620. 1 hit.
    HAMAPiMF_00123. Arg_tRNA_synth.
    InterProiIPR001412. aa-tRNA-synth_I_CS.
    IPR001278. Arg-tRNA-ligase.
    IPR005148. Arg-tRNA-synth_N.
    IPR008909. DALR_anticod-bd.
    IPR014729. Rossmann-like_a/b/a_fold.
    IPR009080. tRNAsynth_1a_anticodon-bd.
    [Graphical view]
    PANTHERiPTHR11956. PTHR11956. 1 hit.
    PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
    PF05746. DALR_1. 1 hit.
    PF00750. tRNA-synt_1d. 1 hit.
    [Graphical view]
    PRINTSiPR01038. TRNASYNTHARG.
    SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
    SM00836. DALR_1. 1 hit.
    [Graphical view]
    SUPFAMiSSF47323. SSF47323. 1 hit.
    SSF55190. SSF55190. 1 hit.
    TIGRFAMsiTIGR00456. argS. 1 hit.
    PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C3KAH3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKDTIRQLIQ QALTQLVNEG VLPEGLTPAI QVENTRDKTH GDFASNIAMM    50
    LSKPAGMKPR DLAEKIIAAL PVDDSVTKAE IAGPGFINFF QNTQALAGRL 100
    DAALADARVG VRKAGPAQRT VVDLSAPNLA KEMHVGHLRS TIIGDGVARV 150
    LEFLGDEVVR QNHVGDWGTQ FGMLMAYLQE NPITSDELSD LENFYRAAKK 200
    RFDESEAFAD RARGLVVKLQ AGDAECLALW TKFKDISLSH CQKIYELLNV 250
    KLTMADVMGE SAYNDDLINV VNDLKAAGML VESNGAQCVF LDEFKNADGE 300
    PLPVIIVKAD GGYLYATTDL AAVRYRSGTL KADRALYFVD QRQALHFQQV 350
    FAVARKAGFV THPMDMEHMG FGTMNGADGR PFKTRDGGTV KLIDLLTEAQ 400
    ERAYTLVKEK NPELAEADLR NIARVVGIGA VKYADLSKHR TSDYSFNFDL 450
    MLNFEGNTAP YLLYAYTRVA GVFRKLGKDF SEVEGQIDLQ ASHEQELAAK 500
    LAQFGEVLNS VGEKGTPHIL CTYLYEVAGL FSSFYENCPI LTADDEAQKQ 550
    SRLRLAALAG RTLKQGLELL GLETLERM 578
    Length:578
    Mass (Da):63,589
    Last modified:June 16, 2009 - v1
    Checksum:i2E955F3D08A3128D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM181176 Genomic DNA. Translation: CAY46678.1.
    RefSeqiWP_012721809.1. NC_012660.1.
    YP_002870081.1. NC_012660.1.

    Genome annotation databases

    EnsemblBacteriaiCAY46678; CAY46678; PFLU_0401.
    GeneIDi7819213.
    KEGGipfs:PFLU0401.
    PATRICi19895012. VBIPseFlu98510_0636.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM181176 Genomic DNA. Translation: CAY46678.1 .
    RefSeqi WP_012721809.1. NC_012660.1.
    YP_002870081.1. NC_012660.1.

    3D structure databases

    ProteinModelPortali C3KAH3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 216595.PFLU0401.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAY46678 ; CAY46678 ; PFLU_0401 .
    GeneIDi 7819213.
    KEGGi pfs:PFLU0401.
    PATRICi 19895012. VBIPseFlu98510_0636.

    Phylogenomic databases

    eggNOGi COG0018.
    KOi K01887.
    OMAi MEHMGFG.
    OrthoDBi EOG6JB13C.

    Family and domain databases

    Gene3Di 1.10.730.10. 1 hit.
    3.30.1360.70. 1 hit.
    3.40.50.620. 1 hit.
    HAMAPi MF_00123. Arg_tRNA_synth.
    InterProi IPR001412. aa-tRNA-synth_I_CS.
    IPR001278. Arg-tRNA-ligase.
    IPR005148. Arg-tRNA-synth_N.
    IPR008909. DALR_anticod-bd.
    IPR014729. Rossmann-like_a/b/a_fold.
    IPR009080. tRNAsynth_1a_anticodon-bd.
    [Graphical view ]
    PANTHERi PTHR11956. PTHR11956. 1 hit.
    Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
    PF05746. DALR_1. 1 hit.
    PF00750. tRNA-synt_1d. 1 hit.
    [Graphical view ]
    PRINTSi PR01038. TRNASYNTHARG.
    SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
    SM00836. DALR_1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47323. SSF47323. 1 hit.
    SSF55190. SSF55190. 1 hit.
    TIGRFAMsi TIGR00456. argS. 1 hit.
    PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SBW25.

    Entry informationi

    Entry nameiSYR_PSEFS
    AccessioniPrimary (citable) accession number: C3KAH3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 22, 2009
    Last sequence update: June 16, 2009
    Last modified: October 1, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Aminoacyl-tRNA synthetases
      List of aminoacyl-tRNA synthetase entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3