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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Pseudomonas fluorescens (strain SBW25)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPFLU216595:G1G1K-582-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:PFLU_0401
OrganismiPseudomonas fluorescens (strain SBW25)
Taxonomic identifieri216595 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002332 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002031021 – 578Arginine--tRNA ligaseAdd BLAST578

Proteomic databases

PRIDEiC3KAH3

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi216595.PFLU0401

Structurei

3D structure databases

ProteinModelPortaliC3KAH3
SMRiC3KAH3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi127 – 137"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

C3KAH3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKDTIRQLIQ QALTQLVNEG VLPEGLTPAI QVENTRDKTH GDFASNIAMM
60 70 80 90 100
LSKPAGMKPR DLAEKIIAAL PVDDSVTKAE IAGPGFINFF QNTQALAGRL
110 120 130 140 150
DAALADARVG VRKAGPAQRT VVDLSAPNLA KEMHVGHLRS TIIGDGVARV
160 170 180 190 200
LEFLGDEVVR QNHVGDWGTQ FGMLMAYLQE NPITSDELSD LENFYRAAKK
210 220 230 240 250
RFDESEAFAD RARGLVVKLQ AGDAECLALW TKFKDISLSH CQKIYELLNV
260 270 280 290 300
KLTMADVMGE SAYNDDLINV VNDLKAAGML VESNGAQCVF LDEFKNADGE
310 320 330 340 350
PLPVIIVKAD GGYLYATTDL AAVRYRSGTL KADRALYFVD QRQALHFQQV
360 370 380 390 400
FAVARKAGFV THPMDMEHMG FGTMNGADGR PFKTRDGGTV KLIDLLTEAQ
410 420 430 440 450
ERAYTLVKEK NPELAEADLR NIARVVGIGA VKYADLSKHR TSDYSFNFDL
460 470 480 490 500
MLNFEGNTAP YLLYAYTRVA GVFRKLGKDF SEVEGQIDLQ ASHEQELAAK
510 520 530 540 550
LAQFGEVLNS VGEKGTPHIL CTYLYEVAGL FSSFYENCPI LTADDEAQKQ
560 570
SRLRLAALAG RTLKQGLELL GLETLERM
Length:578
Mass (Da):63,589
Last modified:June 16, 2009 - v1
Checksum:i2E955F3D08A3128D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM181176 Genomic DNA Translation: CAY46678.1
RefSeqiWP_012721809.1, NC_012660.1

Genome annotation databases

EnsemblBacteriaiCAY46678; CAY46678; PFLU_0401
KEGGipfs:PFLU_0401
PATRICifig|216595.4.peg.636

Similar proteinsi

Entry informationi

Entry nameiSYR_PSEFS
AccessioniPrimary (citable) accession number: C3KAH3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: June 16, 2009
Last modified: May 23, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

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