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C3KAH3 (SYR_PSEFS) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:PFLU_0401
OrganismPseudomonas fluorescens (strain SBW25) [Complete proteome] [HAMAP]
Taxonomic identifier216595 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length578 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 578578Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000203102

Regions

Motif127 – 13711"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
C3KAH3 [UniParc].

Last modified June 16, 2009. Version 1.
Checksum: 2E955F3D08A3128D

FASTA57863,589
        10         20         30         40         50         60 
MKDTIRQLIQ QALTQLVNEG VLPEGLTPAI QVENTRDKTH GDFASNIAMM LSKPAGMKPR 

        70         80         90        100        110        120 
DLAEKIIAAL PVDDSVTKAE IAGPGFINFF QNTQALAGRL DAALADARVG VRKAGPAQRT 

       130        140        150        160        170        180 
VVDLSAPNLA KEMHVGHLRS TIIGDGVARV LEFLGDEVVR QNHVGDWGTQ FGMLMAYLQE 

       190        200        210        220        230        240 
NPITSDELSD LENFYRAAKK RFDESEAFAD RARGLVVKLQ AGDAECLALW TKFKDISLSH 

       250        260        270        280        290        300 
CQKIYELLNV KLTMADVMGE SAYNDDLINV VNDLKAAGML VESNGAQCVF LDEFKNADGE 

       310        320        330        340        350        360 
PLPVIIVKAD GGYLYATTDL AAVRYRSGTL KADRALYFVD QRQALHFQQV FAVARKAGFV 

       370        380        390        400        410        420 
THPMDMEHMG FGTMNGADGR PFKTRDGGTV KLIDLLTEAQ ERAYTLVKEK NPELAEADLR 

       430        440        450        460        470        480 
NIARVVGIGA VKYADLSKHR TSDYSFNFDL MLNFEGNTAP YLLYAYTRVA GVFRKLGKDF 

       490        500        510        520        530        540 
SEVEGQIDLQ ASHEQELAAK LAQFGEVLNS VGEKGTPHIL CTYLYEVAGL FSSFYENCPI 

       550        560        570 
LTADDEAQKQ SRLRLAALAG RTLKQGLELL GLETLERM 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM181176 Genomic DNA. Translation: CAY46678.1.
RefSeqYP_002870081.1. NC_012660.1.

3D structure databases

ProteinModelPortalC3KAH3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING216595.PFLU0401.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAY46678; CAY46678; PFLU_0401.
GeneID7819213.
KEGGpfs:PFLU0401.
PATRIC19895012. VBIPseFlu98510_0636.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
KOK01887.
OMAMEHMGFG.
OrthoDBEOG6JB13C.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_PSEFS
AccessionPrimary (citable) accession number: C3KAH3
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: June 16, 2009
Last modified: May 14, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries