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C3K6D9 (C3K6D9_PSEFS) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylamine--glycine ligase HAMAP-Rule MF_00138
EC=6.3.4.13 HAMAP-Rule MF_00138
Alternative name(s):
GARS HAMAP-Rule MF_00138
Glycinamide ribonucleotide synthetase HAMAP-Rule MF_00138
Phosphoribosylglycinamide synthetase HAMAP-Rule MF_00138
Gene names
Name:purD HAMAP-Rule MF_00138 EMBL CAY46880.1
Ordered Locus Names:PFLU_0611 EMBL CAY46880.1
OrganismPseudomonas fluorescens (strain SBW25) [Complete proteome] [HAMAP] EMBL CAY46880.1
Taxonomic identifier216595 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas ›

Protein attributes

Sequence length430 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N(1)-(5-phospho-D-ribosyl)glycinamide. HAMAP-Rule MF_00138

Cofactor

Binds (magnesium or manganese,ion) per subunit By similarity. HAMAP-Rule MF_00138

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2. HAMAP-Rule MF_00138

Sequence similarities

Belongs to the GARS family. HAMAP-Rule MF_00138

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00138

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain108 – 315208ATP-grasp By similarity HAMAP-Rule MF_00138
Nucleotide binding134 – 19562ATP By similarity HAMAP-Rule MF_00138

Sites

Metal binding2851Magnesium or manganese By similarity HAMAP-Rule MF_00138
Metal binding2871Magnesium or manganese By similarity HAMAP-Rule MF_00138

Sequences

Sequence LengthMass (Da)Tools
C3K6D9 [UniParc].

Last modified June 16, 2009. Version 1.
Checksum: C1FE4308CD08D91C

FASTA43045,423
        10         20         30         40         50         60 
MNVLIIGSGG REHALAWKVA QDPRVQKVFV APGNAGTAIE AKCENVAIDV LALEQLADFA 

        70         80         90        100        110        120 
EKNVSLTIVG PEVPLVAGVV DLFRSRNLDC FGPTAGAAQL EGSKAFTKDF LARHKIPTAD 

       130        140        150        160        170        180 
YQNFTEIEPA LAYLREKGAP IVIKADGLAA GKGVIVAMTL QEAEDAVRDM LAGNAFGDAG 

       190        200        210        220        230        240 
SRVVIEEFLD GEEASFIVMV DGKNVLPMAT SQDHKRVGDG DTGPNTGGMG AYSPAPVVTA 

       250        260        270        280        290        300 
DVHQRVMDLV IWPTVRGMAD EGNVYTGFLY AGLMIDKAGN PKVIEFNCRF GDPETQPVML 

       310        320        330        340        350        360 
RLQSSLVLLV EAALAQALDK VEAQWDPRPS VGIVLAAGGY PADYAKGDVI EGLDAAATLE 

       370        380        390        400        410        420 
GKVFHAGTAL KDGKVVTAGG RVLCATAMGA SVDAAQQQAY TLAAKIDWNG CFYRKDIGYR 

       430 
AIARERGENS

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM181176 Genomic DNA. Translation: CAY46880.1.
RefSeqYP_002870279.1. NC_012660.1.

3D structure databases

ProteinModelPortalC3K6D9.
ModBaseSearch...

Protein-protein interaction databases

STRING216595.PFLU0611.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAY46880; CAY46880; PFLU_0611.
GeneID7819105.
KEGGpfs:PFLU0611.
PATRIC19895436. VBIPseFlu98510_0846.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0151.
KOK01945.
OMAMGAYTPL.
ProtClustDBPRK00885.

Enzyme and pathway databases

UniPathwayUPA00074; UER00125.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
3.90.600.10. 1 hit.
HAMAPMF_00138. GARS.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR016185. PreATP-grasp_dom.
IPR020561. PRibGlycinamid_synth_ATP-grasp.
IPR000115. PRibGlycinamide_synth.
IPR020560. PRibGlycinamide_synth_C-dom.
IPR020559. PRibGlycinamide_synth_CS.
IPR020562. PRibGlycinamide_synth_N.
IPR011054. Rudment_hybrid_motif.
[Graphical view]
PfamPF01071. GARS_A. 1 hit.
PF02843. GARS_C. 1 hit.
PF02844. GARS_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. PreATP-grasp-like. 1 hit.
SSF51246. Rudmnt_hyb_motif. 1 hit.
TIGRFAMsTIGR00877. purD. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00184. GARS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC3K6D9_PSEFS
AccessionPrimary (citable) accession number: C3K6D9
Entry history
Integrated into UniProtKB/TrEMBL: June 16, 2009
Last sequence update: June 16, 2009
Last modified: May 1, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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